“…For intermediate treatment the PEE protocol has to be tuned in dependence on the location within the process. Optimization of PEE protocols is not an easy task, and it requires accounting for the many side effects such as shockwaves, ohmic heating, electrowetting, change in protein pattern of cells, generation of reactive electrode byproducts, and composition of a treated raw substrate (Pliquett 2015). Consequently, further investigations should be carried out for thorough adaptation of PEE protocols accounting for the target products, types of lignocellulosic biomass, and location of PEE within the biorecovery process.…”