Perspectives of intellectual disability in India: epidemiology, policy, services for children and adults

Girimaji, Satish Chandra; Srinath, Shoba

doi:10.1097/yco.0b013e32833ad95c

Cited by 41 publications

(21 citation statements)

References 14 publications

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“…The multicultural, multi-ethnic, and metalinguistic nature of India makes it a difficult task for drawing generalizations about intellectual disability. It is due to the paucity of available data sources and their accessibility [12].…”

Section: Biomedical Research 2018; 29 (15): 3135-3143mentioning

confidence: 99%

Genotyping and clinical characteristics screening of children with intellectual disability in Western India

Khimsuriya¹,

Kharod²,

Chauhan³

2018

biomedicalresearch

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Background: The RhoGTPases (ARHGEF6, OPHN1 and PAK3) are key signaling proteins, and can interrelate extracellular and intracellular signals to sort out changes in the actin cytoskeleton of neuronal network connectivity. IL1RAPL2 is a member of Interleukin 1 receptor family that is expressed at high level in post-natal brain structures involved in the hippocampal memory system. The mutations of these genes have been reported to cause intellectual disability (ID). Therefore, this study is conducted to scrutinize distinctive distributions of genomic variations on West Indian population. Subjects and methods: The genotyping for determination of SNPs associated with X-linked genes (rs35747426 in ARHGEF6, rs121434612 in PAK3, rs199985543 in OPHN1 and rs9887672 in IL1RAPL2) was performed in phenotypically screened 116 intellectually disabled and 100 healthy children by PCR-RFLP method. Results: It has identified that allelic frequencies for rs199985543 and rs9887672 are seen progressively present in the disease group, indicating a significant level of association with ID in Gujarat population. The multifactor dimensionality reduction (MDR), SNP-SNP genotype models are resulted with a relationship of ID if there should be an occurrence of the OPHN1 and IL1RAPL2 gene variants. Additionally, rs199985543 was analyzed for OPHN1 protein structure and stability prediction, which results damaging effect to the protein. Surprisingly, no variation was found for rs35747426 ARHGEF6 and rs121434612 PAK3 polymorphisms in the present study population. Conclusion: This phenotype-genotype relationship has a solid and measurable connection according to the carrier genotypes of the variations and different types of ID, that confirm the mutation in OPHN1 and IL1RAPL2 genes permit serious attention for disease risk.

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Section: Biomedical Research 2018; 29 (15): 3135-3143mentioning

confidence: 99%

Genotyping and clinical characteristics screening of children with intellectual disability in Western India

Khimsuriya¹,

Kharod²,

Chauhan³

2018

biomedicalresearch

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“…O f course, this then has other implications. It is necessary to take into account the high degree of burden on carers of mental health patients (Kumar, Verm, Sinha, & Chittaranjan, 2004), including carer distress and stress (Girimaji & Srinath, 2010), and compassion fatigue: a phenomenon which is a feature of caring in many helping professions (Sabo, 2011).…”

Section: India and Community Mental Healthmentioning

confidence: 99%

Social and political perspectives on the psychotherapy and counselling profession: Returning caravelles

Lees

Macaskie

Freshwater

2014

European Journal of Psychotherapy & Counselling

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The counselling and psychotherapy profession is changing. For the first time in its history, it has begun to receive substantial Government funding in the UK and it also has to contend with the principles o f evidence-based practice and the policies o f the New Public Management systems in many countries. This paper argues that such recent developments present chal lenges to the profession's historical apolitical standpoint. More importantly, it argues that the present social and political climate offers many opportu nities such as the possibility o f learning from psychosocial practices in other countries. The paper will look, in particular, at what can be learned from Latin America and India where mental health care and psychological therapy have adopted grassroots involvement, health-focused approaches and innovatory therapeutic methods.

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“…The National Sample Survey Organization (NSSO) estimates that, currently, 1.8% of the Indian population is disabled, yet the data may not be completely accurate as those with a mild degree of disability remain unidentified. A wide variation in prevalence of intellectual disability has been observed (1/1,000 to 32/1,000) depending on the case definition, methodology, and population selected (Girimaji and Srinath, 2010).…”

Section: Introductionmentioning

confidence: 99%

Exploring Parental Perceptions and Concerns About Sexuality and Reproductive Health of Their Child With Intellectual and Developmental Disability (IDD) in Mumbai

Menon

Sivakami

2019

Front. Sociol.

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In India, sexuality is defined by society, which considers it as a taboo and is usually restricted to sex and related issues like sexual abuse, safe sex, unwanted pregnancy, etc. For a person with disability, sexual desires and wish for parenthood are considered as uncommon. Persons with intellectual and developmental disability (IDD) are characterized by subnormal intelligence, which may partially or totally restrict the person's ability to perform day-to-day activities and take life decisions. Thus, perceptions of primary caregivers, who take decisions on behalf of the person with IDD, have an important role in their life. The aim of the study is to understand parents' perceptions and concerns about the sexuality and reproductive health of their child with an IDD. The study adopted a qualitative methodology wherein 14 primary caregivers of individuals with IDD belonging to different socio-economic and demographic backgrounds were interviewed in Mumbai. The common perceptions were that puberty is expected, sexual behavior is unexpected, and there is a hope for cure. The reaction to puberty onset appeared to vary with the gender of the child. Puberty onset was often seen as an enabling factor for marriage especially among parents of female child. Marriage and/or childbirth was perceived as a possible cure for IDD by some parents. The dominant parental concerns were found to be safety, early onset of puberty, perception of child's action by others, and concerns about the child's family life. These concerns were also found to vary with the gender of the child, type of disability, and the socio-economic status of the family. Some of the perceptions about sexuality were shaped by the primary caregivers' concern for the individual with IDD.

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Perspectives of intellectual disability in India: epidemiology, policy, services for children and adults

Cited by 41 publications

References 14 publications

Genotyping and clinical characteristics screening of children with intellectual disability in Western India

Genotyping and clinical characteristics screening of children with intellectual disability in Western India

Social and political perspectives on the psychotherapy and counselling profession: Returning caravelles

Exploring Parental Perceptions and Concerns About Sexuality and Reproductive Health of Their Child With Intellectual and Developmental Disability (IDD) in Mumbai

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