PERSPECTIVES INTERNATIONALES : Liens entre les variables démographiques, économiques et cliniques et les symptômes rapportés par les patients en cours de traitement contre le cancer

Kolankiewicz, Adriane Cristina Bernat; Magnago, Tânia Solange Bosi de Souza; Dullius, Ângela Isabel dos Santos; Domenico, Edvane Birelo Lopes De

doi:10.5737/23688076274375385

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“…Female predominance in overall cancer diagnosis was observed in the DRC, a similar trend was also observed in Brazil[ 18 ]. The cascade of sexual hormone activity, in particular estrogens and the aromatization of androgens via Mitogen-activated protein kinase, causing the decline of immune cells and promoting the proliferation of cancer cells and the inhibition of apoptotic activity can explain the female predominance[ 19 , 20 ].…”

Section: Discussionsupporting

confidence: 68%

Proportion of thyroid cancer and other cancers in the democratic republic of Congo

Bukasa-Kakamba,

Bangolo,

Bayauli

et al. 2023

World J Exp Med

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BACKGROUND Cancer diagnosis is increasing around the world and in the Democratic Republic of the Congo (DRC). The proportion of thyroid cancer has increased over the past three decades. There are very few studies on cancer epidemiology, and in particular on thyroid cancer in the DRC. AIM To establish the most recent proportion of thyroid cancer in the DRC compared to other cancers. METHODS This is a retrospective and descriptive study of 6106 consecutive cancer cases listed in the pathological registers of 4 Laboratories in the city of Kinshasa. This study included all cancer cases recorded in the registers between 2005 and 2019. RESULTS From a sample of 6106 patients, including all cancer types, 68.3% cases were female and 31.7% were male. Breast and cervical cancer were the most common types of cancer in women and, prostate and skin cancer were the most common types in men. Thyroid cancer was sixth in proportion in women and eleventh in men compared to all cancers. Papillary carcinoma was the most common of thyroid cancers. Rare cancers such as anaplastic and medullary thyroid carcinomas had a proportion of 7% and 2%, respectively. CONCLUSION Newer diagnostic tools led to a surge in cancer diagnoses in the DRC. Thyroid cancer has more than doubled its proportion over the last several decades in the country.

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Section: Discussionsupporting

confidence: 68%