Abstract:How these techniques coupled, high-performance liquid chromatography and mass spectrometry (LC-MS), revolutionized the field of chemical analysis. For a long time, the field of instrumental chemical analysis was limited, as we could not reliably quantify low-concentration substances in complex matrices. This is certainly one of the main advantages of coupling these techniques. In this perspective chapter, the advantages and limitations of the LC-MS system will be presented, sample preparation for this type of … Show more
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