Personalized stimulation therapies for disorders of consciousness: a computational approach to inducing healthy-like brain activity based on neural field theory
Daniel Polyakov,
P.A. Robinson,
Eli J. Müller
et al.
Abstract:Disorders of consciousness (DoC) pose significant challenges in neurology. Conventional neuromodulation therapies for DoC have exhibited limited success, with varying effectiveness among patients. In this study, we introduce a computational approach for constructing personalized stimulus signals capable of inducing healthy-like neural activity patterns in DoC patients. Leveraging a simplified brain model based on neural field theory, we fit this model to the power spectrum of a patient with DoC and derive a pe… Show more
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