Personalized Skin Care Service Based on Genomics

Russian Journal of Physiotherapy, Balneology and Rehabilitation

Gerasimenko²

2022

BACKGROUND: Recently, there has been an increase in early complications after localized exposure to low temperatures (cryolipolysis) for the treatment of localized fat deposition. Carboxytherapy is a method that improves the condition of the microcirculatory bed and reduces swelling. AIM: to develop and evaluate the use of a personalized method of injection carboxytherapy in patients with adverse events (edema and neuropathy) after hardware methods of correction (cryolipolysis) of local fat deposits. MATERIAL AND METHODS: The study involved 45 patients aged 3243 years with a diagnosis of "E65 Localized fat deposition", who received early complications (local edema and a change in sensitivity at the site of exposure to the cryopapillary ― in the sub-umbilical region) after the cryolipolysis procedure (hardware non-surgical correction of local fat deposits). Before the start of treatment, all patients underwent genetic testing according to the "Cosmetology" panel. Three groups were identified, which received injection carboxytherapy locally, paravertebral in the projection of the lumbosacral region, or a combination of both. RESULTS: When analyzing data after a course of treatment, patients with an extended carboxytherapy protocol showed a significant improvement in the quality of life, both in the immediate and in the long-term study period. This was expressed in a statistically significant decrease in intradermal edema and a rapid regression of the pain syndrome in the main group compared to other study groups. CONCLUSION: In patients with early local complications after cryolipolysis, the use of injection carboxytherapy is justified not only locally but also paravertebral, which significantly reduces the recovery period, contributes to a more rapid reduction of local edema and neuropathy phenomena, and also allows obtaining a stable clinical result. Personalized injection carboxytherapy is an effective factor in the relief of complications after cryolipolysis.

unclassified

Personalized injectional carboxytherapy for patients with early complications after low-temperature hardware cosmetic procedures

Russian Journal of Physiotherapy, Balneology and Rehabilitation

Gerasimenko²

2022

Personalized physiotherapy of patients with late complications after the introduction of lip fillers

Russian Journal of Physiotherapy, Balneology and Rehabilitation

Gerasimenko

2022

BACKGROUND: Lip contouring with preparations based on synthetic hyaluronic acid is one of the most popular cosmetic procedures. But in recent years, there has been an explosive increase in the number of complications. There are many physiotherapeutic methods for the treatment of late complications of lip contouring. However, currently there are no differentiated approaches to the choice of physiotherapy techniques and their combination with each other, depending on the nature of the filler and the clinical and functional picture of the complication. AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of lip fillers, taking into account their genetic predisposition. MATERIAL AND METHODS: The study involved 52 patients aged 3042 years with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local swelling, dry and pale lip skin, filler contouring, soreness, sensitivity change) at the filler injection site. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received physico-pharmacological methods: laserophoresis of longidase, diadinamophoresis of collagenase or a combination of them in the lip area at the filler injection site. RESULTS: When analyzing the data after the course of treatment, patients with the combined protocol showed a significant improvement in the quality of life, both in the near and long-term research period. This was expressed in a statistically significant decrease in intradermal edema, rapid regression of pain syndrome and more accelerated biodegradation of the superficially injected filler in the main group compared to other study groups/ CONCLUSION: In patients with late local complications after the introduction of hyaluronic acid fillers, the combined protocol with the inclusion of laser-phoresis of longidase and collagenase diadinamophoresis significantly shortens the recovery period, contributes to a faster reduction of local edema, pain, neuropathy phenomena, accelerated biodegradation of the superficially injected filler, and also allows for a stable clinical result. Personalized physiotherapy is an effective factor in relieving complications after lip contouring.

Personalized method of treatment of patients with complications after contouring of the nasolacrimal sulcus

Russian Journal of Physiotherapy, Balneology and Rehabilitation

2023

BACKGROUND: Contouring of the nasolacrimal sulcus area is becoming an increasingly popular procedure due to the rapid onset of a pronounced aesthetic result, however, in recent years there has been an increase in the pool of complications both in the early and late post-injection recovery period. At the same time, there are no differentiated approaches to the choice of physiotherapy techniques and their combinations depending on the genetic profile of the patient and the clinical and functional picture of the complication. AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of fillers based on stabilized hyaluronic acid, taking into account their genetic predisposition. MATERIAL AND METHODS: The analyzed data of the study of 47 patients, average age 35.710.2, with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local edema, filler contouring, sensitivity change at the filler injection site) after the introduction of a filler based on stabilized hyaluronic acid in the nasolabial furrow area. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received longidase diadinamophoresis, injection carboxytherapy of the nasolacrimal sulcus area or a combination of the above techniques. RESULTS: When using a combined course of longidase diadinamophoresis and injection carboxytherapy, there was a significant decrease in clinical manifestations in the form of conturation, local edema and neuropathy, the psychoemotional state of patients stabilized. In addition, the therapeutic complex significantly accelerated the biodegradation of the filler and has a restructuring effect on the skin of the nasolacrimal furrow, reducing the thickness of the dermis. increasing the density coefficient of the dermis and accelerating the biodegradation of the superficially injected compared to other study groups. CONCLUSION: The personalized combined use of the method, including a course of longidase diadinamophoresis and injectable carboxytherapy for the correction of complications of contouring of the nasolacrimal sulcus area with fillers based on stabilized hyaluronic acid in the form of local edema, neuropathy and filler contouring, is a highly effective treatment method, which is confirmed by the relief of clinical symptoms, acceleration of biodegradation of the drug and improvement of the quality of life of patients.