Personalized medicine for asthma in tropical regions

Caraballo, Luis; Acevedo, Nathalie; Zakzuk, Josefina

doi:10.1097/aci.0000000000000628

Cited by 2 publications

(2 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Allergic diseases, including asthma, are ecological problems where the environment selects genetically susceptible individuals that could be affected. The genetic component has not been resolved and the current information is not yet useful for predicting the disease and apply pharmacogenomics criteria (9). Among a wide variety of environmental risk factors, inflammation from exposure to allergens is critical for the inception and triggering of symptoms.…”

Section: The Rising Of Precision Allergologymentioning

confidence: 99%

Are the Terms Major and Minor Allergens Useful for Precision Allergology?

et al. 2021

Self Cite

View full text Add to dashboard Cite

Section: The Rising Of Precision Allergologymentioning

confidence: 99%

Are the Terms Major and Minor Allergens Useful for Precision Allergology?

et al. 2021

Self Cite

View full text Add to dashboard Cite

“…Regarding the diagnosis of allergy in the tropics, in their paper, Mourao et al demonstrate that allergen conjunctival provocation test is safe and reproducible if standardized allergens are available. They use a conjunctival provocation test to define the clinical impact of sensitization to B. tropicalis in patients with allergic rhinoconjunctivitis; which is an advance in defining the allergenic activity of allergens and is an important step for obtaining an appropriate diagnostic tools for precision allergology in the tropics ( 6 ).…”

mentioning

confidence: 99%

Editorial: Allergens and Allergic Sensitization in Asia and the Tropics

Caraballo

2021

Front. Allergy

Self Cite

View full text Add to dashboard Cite

Editorial on the Research Topic Allergens and Allergic Sensitization in Asia and the TropicsThe inception and clinical symptoms of allergic diseases are highly dependent on the environment, which makes the existence of a single pathogenesis for all these processes unlikely. Therefore, the search for common or specific components, whether genetic or environmental, will provide important information about basic mechanisms, phenotype characterization, and personalized management; and for this, nothing better than investigating the pathophysiological and epidemiological contrasts of allergies between populations with different genetic backgrounds or between populations with great environmental differences.The tropical region has been a traditional source of discoveries from foreign and native scientists, and nowadays interesting projects of scientific groups are exploring several aspects of allergic diseases, among them the patterns of sensitization to common allergens and their impact in the disease manifestations, diagnosis, and treatment. These groups take advantage of known aspects of tropical zones such as their natural characteristics of climate and geographical location, their cultural aspects and the fact that most of the countries are not industrialized.Besides, Asia is a continent with industrialized temperate and tropical countries, as well as important environmental and cultural particularities that could also influence the development of allergic diseases and, of course, these aspects are currently investigated by several groups from this continent, which are collecting valuable data to resolve recognized unmet needs. In fact, while allergic sensitization and the nature of allergenic sources have been extensively characterized in western industrialized countries, such exhaustive analysis is quite lacking and remains to be broadly performed for Asian and tropical countries.This "Research Topic Allergens and Allergic Sensitization in Asia and the Tropics" includes several representative papers on this underexplored field. Here, different peculiarities of allergic problems in Asia and the Tropics are analyzed, which will surely serve as the basis for making comparisons that help to increase knowledge about their pathogenesis.Three of these works confirm that patterns of sensitization to pollens, indoor allergens, and food in Asia have regional characteristics that make a difference from western countries. For example, in Korea (Jeong and Park), sawtooth oak, and birch pollens in the spring in conjunction with weed pollens of mugwort, ragweed, and Japanese hop are the main causes of seasonal allergic rhinitis. Among food allergens, the sensitization to silkworm pupa and buckwheat is also common in Korean patients. Interestingly, honeybee venom due to apitherapy is an important cause of anaphylaxis. In a study from Thailand (Katel et al.), an Asian tropical country, indoor and outdoor aeroallergen sensitization, as detected by skin test, was observed in 32 and 7.9% of adult allergic rhinitis patients, respect...

show abstract

Personalized medicine for asthma in tropical regions

Cited by 2 publications

References 65 publications

Are the Terms Major and Minor Allergens Useful for Precision Allergology?

Are the Terms Major and Minor Allergens Useful for Precision Allergology?

Editorial: Allergens and Allergic Sensitization in Asia and the Tropics

Contact Info

Product

Resources

About