Personality characteristics of women before and after recovery from an eating disorder

Klump, Kelly L.; Strober, Michael; Bulik, Cynthia M.; Thornton, Laura M.; Johnson, Craig; Devlin, Bernie; Fichter, Manfred M.; Halmi, Katherine A.; Kaplan, Allan S.; Woodside, D. Blake; Crow, Scott J.; Mitchell, James E.; Rotondo, Alessandro; Keel, Pamela K.; Berrettini, Wade H.; Plotnicov, Katherine; Pollice, Christine; Lilenfeld, Lisa R.; Kaye, Walter H.

doi:10.1017/s0033291704002442

Cited by 168 publications

(141 citation statements)

References 49 publications

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“…Finally, dysthymia and OCD were reported significantly more often in probands with PAN than in those with RAN. Together these findings are consistent with observations 34 that the presence of binge eating and purging is associated with greater comorbidity and underscore the importance of developing analytic plans for linkage that carefully attend to the presence of binge eating in this sample.…”

Section: Resultssupporting

confidence: 87%

The genetics of anorexia nervosa collaborative study: Methods and sample description

Kaye

Bulik

Plotnicov

et al. 2008

Intl J Eating Disorders

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These results provide context for the genotyping of the first 200 families by the Center for Inherited Disease Research. We will analyze our first 200 families for linkage, complete recruitment of roughly 400 families, and then perform final linkage analyses on the complete cohort. DNA, genotypes, and phenotypes will form a national eating disorder repository maintained by NIMH and available to qualified investigators.

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Section: Resultssupporting

confidence: 87%

The genetics of anorexia nervosa collaborative study: Methods and sample description

Kaye

Bulik

Plotnicov

et al. 2008

Intl J Eating Disorders

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“…Studies comparing actively ill with recovered individuals have indicated that anxiety and certain temperamental traits persist beyond recovery. 37,38 Based on our sample, individuals with a diagnosis of PAN have a higher likelihood of exercising excessively and are therefore more likely to have the associated clinical and personality variables. These results suggest that excessive exercise may be a central strategy that contributes to maintenance of low BMI in patients with AN.…”

Section: Resultsmentioning

confidence: 99%

Features associated with excessive exercise in women with eating disorders

Shroff

Reba

Thornton

et al. 2006

Intl J Eating Disorders

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“…Someone with this diagnosis is frequently constrained, conforming, obsessional, rigid, and perfectionistic" (p. S69). To demonstrate, we present a vignette of an individual with AN ( Figure 2) drawn from an historical account from 1866 (cited in Brumberg, 1988) to highlight features extensively documented in AN both premorbidly and following weight restoration: cognitive and behavioral rigidity (Anderluh et al, 2003;, perfectionism (Bastiani, Rao, Weltzin, & Kaye, 1995;Bulik et al, 2003;Halmi et al, 2000;Woodside et al, 2002), social withdrawal (Diaz-Marsa, Carrasco, & Saiz, 2000; I. C. Gillberg et al, 1995;Godart et al, 2004;Holliday, Uher, Landau, Collier, & Treasure, 2006;Karwautz, Troop, Rabe-Hesketh, Collier, & Treasure, 2003;Kaye et al, 2004), constriction (Geller, Cockell, Hewitt, Goldner, & Flett, 2000), and harm avoidance (Diaz-Marsa et al, 2000;Klump et al, 2000Klump et al, , 2004. In fact, the reliable presentation of this behavioral and personality cluster has been demonstrated to add to the incremental validity of diagnostic accuracy (Westen & Harnden-Fischer, 2001).…”

Section: Overview Of the Phenotypic Expression Of Anmentioning

confidence: 99%

Anorexia nervosa and autism spectrum disorders: Guided investigation of social cognitive endophenotypes.

Zucker¹,

Losh²,

Bulik³

et al. 2007

Psychological Bulletin

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Death by suicide occurs in a disproportionate percentage of individuals with anorexia nervosa (AN), with a standardized mortality ratio indicating a 57-fold greater risk of death from suicide relative to an age-matched cohort. Longitudinal studies indicate impaired social functioning increases risk for fatal outcomes, while social impairment persists following recovery. Study of social cognition in AN may elucidate impaired processes that may influence therapeutic efficacy. Symptoms of autism spectrum disorders (ASD) are overrepresented in those who evidence a chronic course. Relative to that in AN, social information processing in ASD is well characterized and may inform systematic study in AN. This article (a) reviews impaired interpersonal processes in AN, (b) compares the phenotype of AN with that of ASD, (c) highlights deficits of social cognitive disturbance in ASD relative to AN, and (d) proposes a new framework to understand the interaction of individuals with AN with their social context.Keywords: anorexia nervosa, social cognition, autism, interpersonal functioning, eating disorders Individuals with anorexia nervosa (AN) have a nearly 12-fold greater risk of death from all causes and a 57-fold greater risk of death from suicide relative to their age-matched peers (Keel et al., 2003). Such troubling statistics speak to the incapacitating, perplexing, and isolating nature of AN, a severe psychiatric illness that negatively impacts the biological, emotional, and psychosocial functioning of both the affected individual and her or his family (Harris & Barraclough, 1998;Treasure, Whitaker, Whitney, & Schmidt, 2005). In fact, AN exacts a toll on the family reported to exceed that experienced by families with a child with a severe psychiatric disorder such as schizophrenia . Although guiding epidemiologic data are currently lacking, there has been increasing concern regarding several notable trends: (a) an upsurge of AN in both younger and older ages than has been previously reported Johnson, Cohen, Kasen, & Brook, 2006;Marcus & Kalarchian, 2003), (b) increased incidence in minority groups hitherto thought protected (Decaluwe, Braet, & Fairburn, 2003;Tanofsky-Kraff et al., 2003), and (c) recent published reports of extensive illness burden among family members Treasure, Whitaker, Whitney, & Schmidt, 2005;Whitney & Eisler, 2005). Such patterns highlight the broad impact of these illnesses and underscore the urgency of alternative approaches to illness management.While advances have been made in the treatment of adolescents with a relatively short duration of illness (Lock & le Grange, 2005), progress in the treatment of adults with AN remains limited, at best (W. S. Agras et al., 2004;Kaplan, 2002). Of note, a report issued by the National Institute of Mental Health (W. S. Agras et al., 2004) emphasized the absence of innovative treatment approaches over the past several decades. This conclusion was recently echoed in an evidence-based review calling for novel intervention strategies that target core biological...

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Personality characteristics of women before and after recovery from an eating disorder

Cited by 168 publications

References 49 publications

The genetics of anorexia nervosa collaborative study: Methods and sample description

The genetics of anorexia nervosa collaborative study: Methods and sample description

Features associated with excessive exercise in women with eating disorders

Anorexia nervosa and autism spectrum disorders: Guided investigation of social cognitive endophenotypes.

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