Personal exposure to fine particulate matter and renal function in children: A panel study

PM2.5 and Serum Metabolome and Insulin Resistance, Potential Mediation by the Gut Microbiome: A Population-Based Panel Study of Older Adults in China

“…2019 ). The response to acute inflammation is dynamic, and it is technically difficult to measure cytokine levels below the detection limit ( Liu et al. 2020a ; Xie et al.…”

Short-term exposure to fine particulate matter and its constituents may affect renal function via oxidative stress: A longitudinal panel study

“…Numerous studies provided epidemiological evidence that PM 2.5 may serve as a risk factor of renal dysfunction ( Mehta et al, 2016 ; Tavera Busso et al, 2018 ; Liu et al, 2020 ; Rahmani Sani et al, 2020 ; Zhao et al, 2020 ; Li et al, 2021 ). Most studies reported the significant associations between PM 2.5 and the kidney indicators of sCr and eGFR among populations.…”

“…Most studies reported the significant associations between PM 2.5 and the kidney indicators of sCr and eGFR among populations. A recent panel study on 135 children aged 4–13 years reported that a 10 μg/m 3 increment of PM 2.5 was related to −1.83% changes in eGFR ( Liu et al, 2020 ). The VA Normative Aging Study reported that per 2.1 μg/m 3 increment in annual average of PM 2.5 was related with 1.87 mL/min/1.73 m 2 declination of eGFR among 669 older adults with an average age of 73.5 ( Mehta et al, 2016 ).…”

“…Another research on rodent models found that sub-chronic exposure to PM 2.5 could lead to elevated blood urea nitrogen (BUN) levels ( Tavera Busso et al, 2018 ). However, most previous research focused on pregnant women ( Zhao et al, 2020 ), children ( Liu et al, 2020 ) or the elderly ( Mehta et al, 2016 ; Fang et al, 2020 ), while the associations among healthy adults was not fully characterized. Additionally, PM 2.5 is a heterogeneous mixture with nephrotoxic constituents, which may contribute to the major association between PM 2.5 and renal dysfunction.…”

Short-term exposure to fine particulate air pollution and emergency department visits for kidney diseases in the Atlanta metropolitan area

“… 20 Another panel study with 105 children 4–13 years of age in Wuhan, China, showed that personal exposure to PM 2.5 was dose-responsive related to decline in eGFR within lag 2 days with the strongest at lag 0 day [−1.69% (95% CI: −2.27%, −1.10%) in eGFR per 10 μg/m 3 increase in PM 2.5 ]. 22 Gu et al 21 and Wei et al 23 reported that short-term (daily) PM 2.5 exposure was associated with increased risks of hospital admission for kidney diseases based on electronic inpatient records in China (all-age) and the United States (age 65 years or older), respectively.…”