2009
DOI: 10.3171/2008.7.jns08287
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Persisting embryonal infundibular recess

Abstract: Persisting embryonal infundibular recess (PEIR) is a rare anomaly of the third ventricular floor that has an unclear pathogenesis. In all 7 previously described cases, PEIR was present in adult patients and was invariably associated with hydrocephalus and, in 4 reported cases, with an empty sella. These associated findings led to speculations about the role of increased intraventricular pressure in the development of PEIR. In the present case, PEIR was found in a 24-year-old man without the presence of hydroce… Show more

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Cited by 16 publications
(8 citation statements)
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“…The distal part of the infundibulum is obliterated and is referred to as the infundibular stem. 10) By the time the fetus reaches 45 mm in length, the distal part of the infundibular sac is obliterated by cellular proliferation 1,2) and ultimately differentiates to form the obliterated part of the infundibulum and the posterior pituitary lobe. 11) In some mammals, such as the cat or the bear, the entire embryonal infundibular recess persist extending through the tubular pituitary stalk to the posterior lobe of the pituitary.…”
Section: Discussionmentioning
confidence: 99%
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“…The distal part of the infundibulum is obliterated and is referred to as the infundibular stem. 10) By the time the fetus reaches 45 mm in length, the distal part of the infundibular sac is obliterated by cellular proliferation 1,2) and ultimately differentiates to form the obliterated part of the infundibulum and the posterior pituitary lobe. 11) In some mammals, such as the cat or the bear, the entire embryonal infundibular recess persist extending through the tubular pituitary stalk to the posterior lobe of the pituitary.…”
Section: Discussionmentioning
confidence: 99%
“…The authors of previous publications proposed that the increased intraventricular pressure developed PEIR, because of the presence of hydrocephalus in the majority of reported patients with PEIR. 1,2,4–8) On the other hand, Steno et al experienced a case of PEIR without hydrocephalus and proposed the etiology of PEIR is a developmental anomaly caused by lack of obliteration of the distal part of the primary diencephalic evagination. 1) In the present case, PEIR was not accompanied by hydrocephalus, which supports the latter hypothesis.…”
Section: Discussionmentioning
confidence: 99%
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“…This is a rare condition with only eight cases reported in world literature. [ 1 ] In previously reported cases, the defect was demonstrated in the third ventricular floor, with the sac descending inferiorly only up to the sella. However, this is the first case of PEIR, with the sac descending into the nasal cavity as pulsatile nasal mass.…”
Section: Introductionmentioning
confidence: 99%