Persistent postural-perceptual dizziness: A functional neuro-otologic disorder

Yagi, Chihiro; Kimura, Akira; Horii, Arata

doi:10.1016/j.anl.2023.12.008

Cited by 2 publications

(5 citation statements)

References 63 publications

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Section: Integrated Research Approachesmentioning

confidence: 99%

“…Promoting interdisciplinary research that integrates neurology, otolaryngology, psychiatry, and rehabilitation sciences is imperative for advancing our understanding of PPPD [32]. The collaboration of experts from these diverse disciplines contributes nuanced perspectives to elucidate the multifaceted nature of PPPD comprehensively [32]. An interdisciplinary approach facilitates a holistic exploration of PPPD, considering not only its physiological underpinnings but also its psychological and rehabilitative aspects [32].…”

Section: Integrated Research Approachesmentioning

confidence: 99%

“…The collaboration of experts from these diverse disciplines contributes nuanced perspectives to elucidate the multifaceted nature of PPPD comprehensively [32]. An interdisciplinary approach facilitates a holistic exploration of PPPD, considering not only its physiological underpinnings but also its psychological and rehabilitative aspects [32]. This collaborative synergy of expertise is crucial for deciphering the complexities of PPPD and holds the potential to generate innovative, patient-centered interventions [32].…”

Section: Integrated Research Approachesmentioning

confidence: 99%

“…An interdisciplinary approach facilitates a holistic exploration of PPPD, considering not only its physiological underpinnings but also its psychological and rehabilitative aspects [32]. This collaborative synergy of expertise is crucial for deciphering the complexities of PPPD and holds the potential to generate innovative, patient-centered interventions [32]. Encouraging interdisciplinary research is instrumental in fostering transformative breakthroughs that not only enhance our understanding of PPPD but also elevate the standard of care provided to individuals contending with this challenging condition [32].…”

Section: Integrated Research Approachesmentioning

confidence: 99%

“…Advances in neuroimaging techniques have revolutionized researchers to explore structural and functional brain changes associated with PPPD [32]. Functional magnetic resonance imaging (fMRI) has been instrumental in uncovering structural changes in the brains of individuals with PPPD [33].…”

Section: Neuroimaging Studiesmentioning

confidence: 99%

See 4 more Smart Citations

Persistent Challenges: A Comprehensive Review of Persistent Postural-Perceptual Dizziness, Controversies, and Clinical Complexities

Madrigal,

Herrón-Arango,

Bedoya

et al. 2024

Cureus

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Persistent postural-perceptual dizziness (PPPD) is a chronic and disabling disorder characterized by persistent dizziness, unsteadiness, and imbalance. It often arises without an identifiable cause and is exacerbated by upright posture, active or passive movement, and exposure to moving or complex visual stimuli. This complex pathophysiology and the psychological dimensions of its symptomatology pose a significant challenge to clinicians. PPPD presents diagnostic challenges and a lack of standardized treatment options, underscoring the need for multidisciplinary approaches encompassing pharmacotherapy, vestibular rehabilitation, and psychological interventions for effective management. Bridging the gaps in understanding PPPD requires collaborative efforts across disciplines, emphasizing integrated research approaches and patient support networks to enhance care and improve outcomes. This review explores the challenges, controversies, and clinical complexities of PPPD, highlighting the importance of a patientcentered approach.

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Section: Integrated Research Approachesmentioning

confidence: 99%

Section: Integrated Research Approachesmentioning

confidence: 99%

Section: Integrated Research Approachesmentioning

confidence: 99%

Section: Integrated Research Approachesmentioning

confidence: 99%

Section: Neuroimaging Studiesmentioning

confidence: 99%

See 3 more Smart Citations

Persistent Challenges: A Comprehensive Review of Persistent Postural-Perceptual Dizziness, Controversies, and Clinical Complexities

Madrigal,

Herrón-Arango,

Bedoya

et al. 2024

Cureus

View full text Add to dashboard Cite

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Comparative study of Cognitive-Behavioral Therapy with Pharmacotherapy for Persistent Postural-Perceptual Dizziness: A Pilot Study

Kang,

Tanaka,

Yagi

et al. 2024

Preprint

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We conducted a non-randomized, open-label, parallel-group study on patients with persistent postural-perceptual dizziness (PPPD) to compare cognitive-behavioral therapy ([CBT] group, n = 20) received a 6-session CBT program with pharmacotherapy ([PT] group, n = 22) received serotonin-related antidepressants. Outcomes were assessed using the Dizziness Handicap Inventory (DHI), the Hospital Anxiety and Depression Scale (HADS), and the Niigata PPPD Questionnaire (NPQ). Assessments were performed before and 3 months post-treatment. There were no significant differences in patients background such as sex, age, precipitating conditions, and vestibular function tests, however, illness duration was significantly longer in the CBT group than the PT group. Both CBT and PT significantly lowered the levels of dizziness-related handicaps in daily life (DHI), depression (HADS-D), anxiety (HADS-A), and symptom exacerbations by triggers (NPQ), while two-way ANOVA revealed no treatment x time interaction. Nonetheless, CBT yielded a larger Hedges’ g effect size in improving DHI, HADS-A and NPQ than PT. While PT is reportedly sometimes discontinued due to adverse events such as vomiting, all patients in the CBT group could complete the program with no adverse effects. CBT is a potential therapy for PPPD which is safe and effective as equal to or greater than PT even for patients with prolonged illness. Clinical trial registration numbers and date of registration: UMIN-CTR: UMIN000054701, 18/06/2024

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Persistent postural-perceptual dizziness: A functional neuro-otologic disorder

Cited by 2 publications

References 63 publications

Persistent Challenges: A Comprehensive Review of Persistent Postural-Perceptual Dizziness, Controversies, and Clinical Complexities

Persistent Challenges: A Comprehensive Review of Persistent Postural-Perceptual Dizziness, Controversies, and Clinical Complexities

Comparative study of Cognitive-Behavioral Therapy with Pharmacotherapy for Persistent Postural-Perceptual Dizziness: A Pilot Study

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