Persistent pollutants: A brief history of the discovery of the widespread toxicity of chlorinated hydrocarbons

Rosner, David J.; Markowitz, Gerald

doi:10.1016/j.envres.2012.08.011

Cited by 59 publications

(26 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Earlier, this impact originated mainly from chlorinated hydrocarbons, i.e., the PCB family of compounds, which included the pesticide dichlorodiphenyltrichloroethane (DDT). Recently, researchers have focused on a number of consumer products that can Responsible editor: Ester Heath * Daniel Junqueira Dorta djdorta@gmail.com interfere in the endocrine system (Rosner and Markowitz 2013). Endocrine disruptors are exogenous substances that alter the functions of the endocrine system and adversely affect the health, growth, reproduction, and progeny of organisms, even at concentrations in the order of microgram and nanogram per liter (Bila and Dezotti 2003).…”

Section: Introductionmentioning

confidence: 99%

A perspective on the potential risks of emerging contaminants to human and environmental health

Pereira

Souza

Bernardes

et al. 2015

Environ Sci Pollut Res

206

View full text Add to dashboard Cite

Technological, agricultural, and medical advances have improved the lifestyle of humankind. However, these advances have caused new problems that affect the environment and future generations. Emerging contaminants display properties such as low degradation potential and environmental persistence. In addition, most contaminants are lipophilic, which culminates in high bioaccumulation. The disposal of pharmaceuticals and personal care products into the environment underlies microbial and bacterial resistance. Plasticizers change several characteristics of industrialized materials, such as flexibility, but they are potentially carcinogenic and disrupt the endocrine system. Pesticides prevent the propagation of numerous kinds of pests; nevertheless, they exert neurotoxic and mutagenic effects, and they impact the environment negatively. Addition of flame retardants to a number of materials prevents flame propagation; however, after their release into the environment, these chemicals may bioaccumulate in organisms and disrupt the endocrine system, too. Surfactants can change the surface and interfacial properties of liquids, but their presence in the environment can interfere with countless enzymes and can even impair the endocrine system of various organisms and induce the feminization of species. Hence, gaining knowledge about emerging contaminants is increasingly important to minimize future damage and enable proper monitoring of each class of compounds in the environment which will help to improve legislation on this matter.

show abstract

Section: Introductionmentioning

confidence: 99%

A perspective on the potential risks of emerging contaminants to human and environmental health

Pereira

Souza

Bernardes

et al. 2015

Environ Sci Pollut Res

206

View full text Add to dashboard Cite

show abstract

“…Chlorinated hydrocarbons and their metabolites and degradation products represent another source of xenoestrogens that persists in the environment (Rosner and Markowitz, 2013). Commercial dichlorodiphenyltrichloroethane (DDT) products typically consist of a mixture of compounds with the p,p9-isomer as the major component (;77%), followed by the o,p9-isomer (;15%).…”

Section: F Xenoestrogensmentioning

confidence: 99%

International Union of Basic and Clinical Pharmacology. XCVII. G Protein–Coupled Estrogen Receptor and Its Pharmacologic Modulators

2015

View full text Add to dashboard Cite

“…The risks and benefits of these must be assessed on a sound scientific basis. Therefore, it is important do a significant reduction in the use of synthetic pesticides under an IPM program (Rosner and Markowitz 2013;Rhodes et al 2013).…”

Section: Introductionmentioning

confidence: 98%

Chemical constituents and biological activities of South American Rhamnaceae

Alarcón

Cespedes‐Acuña

2015

Phytochem Rev

View full text Add to dashboard Cite

Secondary metabolites have diverse functions into plants. These functions are products of the coevolution which result in synthesis of constitutive and/or induced chemical defense generated for protection against to different phytopathogenic attack. Many phytochemical studies are biodirected with the aim of finding biopesticides of botanical origins. Some taxa of Americas such as Rhamnaceae family are toxic to insects, fungi and several bacteria strains, and these effects has been associated with the presence of alkaloids, phenolics and terpenes. The natural compounds that have been isolated represent a valuable resource for future studies of plant chemical defense and the role of these substances in chemical ecology.Here are show recent advances in the phytochemistry and biological activities of selected members of Rhamnaceae from Latin-America.

show abstract

Persistent pollutants: A brief history of the discovery of the widespread toxicity of chlorinated hydrocarbons

Cited by 59 publications

References 6 publications

A perspective on the potential risks of emerging contaminants to human and environmental health

A perspective on the potential risks of emerging contaminants to human and environmental health

International Union of Basic and Clinical Pharmacology. XCVII. G Protein–Coupled Estrogen Receptor and Its Pharmacologic Modulators

Chemical constituents and biological activities of South American Rhamnaceae

Contact Info

Product

Resources

About