Persistent Pharyngeal Membrane

Oropharyngeal atresia in a preterm infant: A case report and review of the literature

“…Oropharyngeal atresia is a rare condition, with 15 previous reports in the literature, 5 of which were (Table 1) [1][2][3][4][5][6][7][8][9][10][11][12][13]. This condition has also previously been reported as ''persistent buccopharyngeal membrane'' in the literature.…”

“…Although a few cases have presented initially with feeding and swallowing difficulties at a few days after delivery without major respiratory problems, most cases have presented a challenge in airway management, many of the patients having [11] 36 Hypomandibular faciocranial dysostosis Prominent labia minora; bicornuate uterus Schimke [9] 35 Hypomandibular faciocranial dysostosis Patent ductus arteriosus Neidich [10] 36 Hypomandibular faciocranial dysostosis Atrial septal defect Flannery [1] 32 Mild mandibulofacial dysostosis, broad nasal bridge, left choana stenotic Vertebral and digital anomalies, low set posteriorly angulated ears Seghers [2] Term None Vertebral and auricular anomalies Longacre [13] Term Partial cleft of soft palate None Bent [5] Term Micrognathia, microglossia None Bent [5] Term None Transposition of the great arteries Lim [7] Term None Atrial septal defect Present case 28 None Ventricular septal defect, vertebral anomalies Takahashi [6] Term None None Agarwal [3] Term None None Agarwal [3] Term None None Hoffman [12] Term None None Chandra [3] Term None None died in the immediate neonatal period due to airway issues, or in the postneonatal period due to pneumonia [1][2][3][4] Two patients that survived had emergent tracheostomies performed soon after delivery [5,6] Other cases have had some communication through the membrane, either through a cleft soft palate or small dehiscence of the membrane [5,13]. Our case represents the first in which there was successful endotracheal intubation through a slit in the persistent membrane.…”

Persistent buccopharyngeal membrane: Report of a case and review of the literature

“…Eight patients were able to breathe easily and presented between 1 day and 3 months of age with dysphagia [2,8,[18][19][20][21]. Physical examination of these patients demonstrated either a partial or total BPM.…”

“…Associated congenital anomalies Verma Transposition of great arteries, patent ductus arteriosus, atrial septal defect Lee [4] Ventricular septal defect, patent ductus arteriosus, vertebral anomalies Kara [3] None Takahashi [5] None Tan [6] Atrial septal defect Ooi [7] None Lim [8] Atrial septal defect, unilateral choanal atresia Thauvin [9] Hypomandibular faciocranial dysostosis Kantaputra [10] Aglossia, micrognathia, microcephaly, absence of mandibular teeth Bent [11] Transposition of great arteries Agarwal [2] None Agarwal [2] None Ludman [12] Hypomandibular faciocranial dysostosis, bicornuate uterus Gartlan [13] Micrognathia, microglossia Schimke [14] Hypomandibular faciocranial dysostosis, patent ductus arteriosus Flannery [15] Mandibulofacial dysostosis, downslanting palpebral fissures, epicanthal folds, broad nasal bridge, costovertebral anomalies Neidich [16] Severe first branchial arch anomalies, atrial septal defect Arcand [17] None Hoffman [18] None Chandra [19] None Seghers [20] Auricular and vertebral anomalies Longacre [21] None Fridenberg [22] None…”