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2017
DOI: 10.1111/vde.12469
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Persistent papilloma treated with cryotherapy in three dogs

Abstract: The apparent resolution of these papilloma lesions with cryotherapy suggests that this may be a useful treatment intervention for persistent canine papilloma lesions. Spontaneous resolution may still have taken place; consequently, large scale clinical trials are required to demonstrate unequivocally that this mode of therapy, as with other therapeutic modalities, is really effective in the treatment of canine papillomatosis.

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Cited by 16 publications
(24 citation statements)
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“…The use of cryotherapy for viral lesions has been successfully documented in both human and veterinary medicine. Cryotherapy intervention in three dogs affected by persistent papilloma utilising a 5–6 freeze‐thaw cycle (15–30 s) was reported to be a highly effective treatment modality 7. Given the severity and extensive nature of the CPV growths, surgically debulking and ablating the growths first provided better penetration for cryotherapy administration.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The use of cryotherapy for viral lesions has been successfully documented in both human and veterinary medicine. Cryotherapy intervention in three dogs affected by persistent papilloma utilising a 5–6 freeze‐thaw cycle (15–30 s) was reported to be a highly effective treatment modality 7. Given the severity and extensive nature of the CPV growths, surgically debulking and ablating the growths first provided better penetration for cryotherapy administration.…”
Section: Discussionmentioning
confidence: 99%
“…The lesions were frozen with liquid nitrogen using a Mini‐Cryogun (Brymill, Vernon, Connecticut, USA). A more aggressive previously described freeze‐thaw cycle technique was used 7. Clindamycin hydrochloride capsules (Ranbaxy) 7.6 mg/kg orally twice daily for 1 week was restarted to prevent secondary infection and interferon was continued.…”
Section: Investigationsmentioning
confidence: 99%
“…The main advantages of LN‐cryotherapy are the selective destruction of diseased tissue without damaging the surrounding normal area and the avoidance of general anaesthesia . In the past, cryosurgery in dogs has been described in sedated or anaesthetized patients . Benign sebaceous or follicular tumours are common in dogs and they can be numerous .…”
Section: Introductionmentioning
confidence: 99%
“…1 In the past, cryosurgery in dogs has been described in sedated or anaesthetized patients. [2][3][4][5] Benign sebaceous or follicular tumours are common in dogs and they can be numerous. 6 Surgery under general anaesthesia is usually suggested to treat these lesions.…”
Section: Introductionmentioning
confidence: 99%
“…Die Prognose ist bei Adenomen gut und bei Karzinomen je nach Ausmaß und Stadium vorsichtig.TherapieBeim Junghund ist meist keine Therapie nötig, da es in der Regel zur Spontanremission kommt[18]. Bei einer Traumatisierung oder beim älteren Hund ist eine (kryo-)chirurgische Therapie indiziert[26]. Umstritten ist die Herstellung einer Autovakzine.…”
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