Persistent Organic Pollutans (Pops) Dan Konvensi Stockholm

Abstract

Persistent organic pollutants (POPs) are toxic chemicals that adversely affect human health and the environment around the world. Because they can be transported by wind and water, most POPs generated in one country can affect people and wildlife far from where they are used and released. They persist for long periods of time in the environment and can accumulate and pass from one species to the next through the food chain. To address this global concern, many countries in the world joined forces with 90 other countries and the European Community to sign a groundbreaking United Nations treaty in Stockholm, Sweden, in May 2001, known as the Stockholm Convention. One of important agreement is all countries agreed to reduce or eliminate the production, use, and/or release of 12 key POPs. The Convention specifies a scientific review process that could lead to the addition of other POPs chemicals of global concern. POPs include a range of substances that include intentionally produced chemicals currently or once used in agriculture, disease control, manufacturing, or industrial processes. Also it can be produced by unintentionally produced chemicals, such as dioxins, that result from some industrial processes and from combustion (for example, municipal and medical waste incineration and backyard burning of trash).

Dampak Dari Persistent Organic Pollutants (Pops) Terhadap Lingkungan Dan Kesehatan Masyarakat

“…Sebagian metabolit ini akan menjadi toksik dan sebagian lagi menjadi karsinogen yang aktif. Kanker yang disebabkan dioksin antara lain dapat berupa kanker paruparu, kanker hati, dan sebagainya, senyawa ini juga dapat merusak fungsi reproduksi (Warlina, 2009).…”

Berdampakkah Cemaran Dioksin Bagi Keadaan Gizi Dan Kesehatan?

“…Senyawa ini berbahaya bagi kesehatan manusia, hewan dan tumbuhan yang dihasilkan dari proses sampingan industry, seperti dioksin/furan atau dari industry itu sendiri seperti Dichloro Diphenyl Trichloroethane (DDT). (Lina Warlina, 2009) Makanan merupakan sumber utama paparan dioksin dan senyawa terkait pada manusia. (Guidance values for dioxins and dioxin-like PCBs', 2015 (Guidance values for dioxins and dioxin-like PCBs ', 2015) Dioksin merupakan kontaminan hidrofobik dan terakumulasi di dalam lemak, dapat berupa polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) dan dioxin-like polychlorinated biphenyls (dl-PCBs).…”

PENGARUH PEMBERIAN EKSTRAK RUMPUT KEBAR (Biophytum petersianum Klotzsch) TERHADAP JUMLAH SEL SERTOLI MENCIT (Mus musculus) YANG DIPAPAR 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN

“…Senyawa kompleks ini kemudian akan masuk ke dalam inti sel (nucleus), dan berikatan dengan DNA (Deoxyribo Nucleic Acid) pada tempat yang spesif dan diikuti dengan translokasi m-RNA (messenger Ribose Nucleic Acid). Senyawa kompleks ini akan mempengaruhi gengen lain, salah satunya gen spesifik P-4501A1 dan menghasilkan produk berupa radikal bebas (ROS) (Warlina, 2009). radikal bebas (ROS) dapat merusak membran sel melalui peroksidasi lipid.…”