“…Many studies have shown that there is a close relationship between SAH and miRNA in a variety of physiological and pathological aspects, such as signal pathway level, cellular level, and so on, and predict that miRNA will become one of the effective methods for the treatment of SAH in the future ( Su et al, 2015 ; Chen et al, 2017 ). It not only participates in inflammation, neuronal apoptosis, synaptic remodeling, and many other cellular functions but also detects the differential expression of miRNA in blood, cerebrospinal fluid (CSF) of SAH patients, and MCA of SAH model in rats ( Kikkawa et al, 2017 ; Sheng et al, 2018a , b ). Many disorders of miRNA expression are involved in the occurrence and development of CVS, and the detection of miRNA in EVs can be used as a new standard to prevent, diagnose, and judge the prognosis of CVS after SAH.…”