Persistent Endemicity of
            <i>Salmonella bongori</i>
            48:z
            <sub>35</sub>
            :− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Giammanco, Giovanni M.; Pignato, Sarina; Mammina, Caterina; Grimont, Francine; Grimont, Patrick A. D.; Nastasi, A; Giammanco, G

doi:10.1128/jcm.40.9.3502-3505.2002

Cited by 49 publications

(34 citation statements)

References 11 publications

(5 reference statements)

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“…Our initial aim was to investigate whether there are uncharacterized elements closely related to SPI-7 within the Salmonella genus and particularly to investigate strains within the species S. bongori, which, until recently, was understudied with regard to its genetic diversity (20). S. bongori is a second species of Salmonella, generally associated with cold-blooded animals, although there are some reports of it causing human infections (22). In total, we screened 66 strains of Salmonella by microarray and draft Illumina sequencing, consisting of 13 strains belonging to subspecies of S. enterica (excluding S. Typhi, S. Paratyphi C, and S. Dublin) and 53 strains of S. bongori.…”

Section: Resultsmentioning

confidence: 99%

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

et al. 2012

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Integrative and conjugative elements (ICEs) are self-mobile genetic elements found in the genomes of some bacteria. These elements may confer a fitness advantage upon their host bacteria through the cargo genes that they carry. Salmonella pathogenicity island 7 (SPI-7), found within some pathogenic strains of Salmonella enterica, possesses features indicative of an ICE and carries genes implicated in virulence. We aimed to identify and fully analyze ICEs related to SPI-7 within the genus Salmonella and other Enterobacteriaceae. We report the sequence of two novel SPI-7-like elements, found within strains of Salmonella bongori, which share 97% nucleotide identity over conserved regions with SPI-7 and with each other. Although SPI-7 within Salmonella enterica serovar Typhi appears to be fixed within the chromosome, we present evidence that these novel elements are capable of excision and self-mobility. Phylogenetic analyses show that these Salmonella mobile elements share an ancestor which existed approximately 3.6 to 15.8 million years ago. Additionally, we identified more distantly related ICEs, with distinct cargo regions, within other strains of Salmonella as well as within Citrobacter, Erwinia, Escherichia, Photorhabdus, and Yersinia species. In total, we report on a collection of 17 SPI-7 related ICEs within enterobacterial species, of which six are novel. Using comparative and mutational studies, we have defined a core of 27 genes essential for conjugation. We present a growing family of SPI-7-related ICEs whose mobility, abundance, and cargo variability indicate that these elements may have had a large impact on the evolution of the Enterobacteriaceae. Bacterial genomes are often represented as a core of conserved genes interspersed with accessory regions which are variably present throughout members of a species. The ability of an organism to sample variation through accessing a pan-genome can be strongly associated with a change in lifestyle or adaptation to a new niche (29). In some cases, acquired accessory functions become fixed and go on to define a particular lineage (30). A classical example of this is the acquisition of the Salmonella pathogenicity islands (SPIs), considered to have been fundamental to the evolution of the genus Salmonella (26). The largest of these islands identified to date is SPI-7, found within the genomes of Salmonella enterica subsp. enterica serovar Typhi (S. Typhi) (52), Salmonella enterica subsp. enterica serovar Paratyphi C (S. Paratyphi C) (43), and some strains of Salmonella enterica subsp. enterica serovar Dublin (S. Dublin) (55). SPI-7 is 120 kb in length and encodes important virulence functions, including the major virulence antigen (Vi) and type IVB pili (24, 52). Additionally, integrated within SPI-7 from strains of S. Typhi is a prophage harboring the type 3 secretion system effector protein-encoding gene sopE (47).SPI-7 possesses many similarities to integrative and conjugative elements (ICEs), a class of self-transmissible elements (7) also known as conjugativ...

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Section: Resultsmentioning

confidence: 99%

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

et al. 2012

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“…Essa espé-cie é rara e nunca havia sido registrado como responsável por infecções em humanos ou animais, mas mostrou-se capaz de causar enterite aguda em crianças e, ocasionalmente, em imunodeficientes adultos e animais no sul da Itália (Giammanco et al, 2002).…”

Section: Pombo Doméstico (Columba Livia)unclassified

O pombo (Columba livia) como agente carreador de Salmonella spp. e as implicações em saúde pública

Rocha-e-Silva

Maciel

Teixeira³

et al. 2014

Arq. Inst. Biol.

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Os pombos domésticos e silvestres estão distribuídos por todo o mundo e carreiam micro-organismos patogênicos ao homem e a outros animais, podendo ser um dos responsáveis pela disseminação de Salmonella spp. Este patógeno gera grande preocupação para a economia mundial, uma vez que cria transtornos para a indústria avícola quando ocorre contaminação dos plantéis e ônus para a saúde pública devido a surtos de infecção alimentar causados por esta bactéria. Dessa forma, objetivou-se realizar um levantamento acerca da participação do pombo doméstico na possível disseminação de Salmonella spp.

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“…Molecular typing by PFGE after digestion of DNA by XbaI showed a banding pattern similar to that of all previously identifi ed S. bongori 48:z35:-. In particular, the DNA restriction pattern proved to be indistinguishable from patterns of the human isolates belonging to the epidemic clusters and of the pigeon isolates (3).…”

mentioning

confidence: 94%

Salmonella bongori48:z₃₅:– in Migratory Birds, Italy

Foti¹,

Daidone²,

Aléo³

et al. 2009

Emerg. Infect. Dis.

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Persistent Endemicity of Salmonella bongori 48:z ₃₅ :− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Cited by 49 publications

References 11 publications

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

O pombo (Columba livia) como agente carreador de Salmonella spp. e as implicações em saúde pública

Salmonella bongori48:z₃₅:– in Migratory Birds, Italy

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Persistent Endemicity of Salmonella bongori 48:z 35 :− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Cited by 49 publications

References 11 publications

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae

O pombo (Columba livia) como agente carreador de Salmonella spp. e as implicações em saúde pública

Salmonella bongori48:z35:– in Migratory Birds, Italy

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Persistent Endemicity of Salmonella bongori 48:z ₃₅ :− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Salmonella bongori48:z₃₅:– in Migratory Birds, Italy