Persistent abnormal left ventricular systolic torsion in dilated cardiomyopathy after partial left ventriculectomy

Setser, Randolph M.; Kasper, J; Lieber, Michael L.; Starling, Randall C.; McCarthy, Patrick M.; White, Richard D.

doi:10.1016/s0022-5223(03)00050-3

Cited by 67 publications

(57 citation statements)

References 30 publications

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“…We propose 'LV solid body rotation' as a new sensitive and specific, objective and quantitative, functional criterion, supplementing the classic subjective morphologic NCCM criteria [8,26,27]. It should be noticed that others, in contrast to our findings, have occasionally described LV solid body rotation in DCM patients [28]. Although it cannot be excluded that in these patients the diagnosis NCCM was overlooked, the true specificity of LV solid body rotation for the diagnosis of NCCM may be lower than that in our study.…”

Section: Discussionmentioning

confidence: 37%

Left ventricular solid body rotation in non‐compaction cardiomyopathy: A potential new objective and quantitative functional diagnostic criterion?

Dalen

Çalışkan

Soliman

et al. 2008

European J of Heart Fail

116

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Background: Left ventricular (LV) twist originates from the interaction between myocardial fibre helices that are formed during the formation of compact myocardium in the final stages of the development of myocardial architecture. Since non-compaction cardiomyopathy (NCCM) is probably caused by intrauterine arrest of this final stage, it may be anticipated that LV twist characteristics are altered in NCCM patients, beyond that seen in patients with impaired LV function and normal compaction. Aims: The purpose of this study was to assess LV twist characteristics in NCCM patients compared to patients with non-ischaemic dilated cardiomyopathy (DCM) and normal subjects. Methods and results:The study population consisted of 10 patients with NCCM, 10 patients with DCM, and 10 healthy controls. LV twist was determined by speckle tracking echocardiography. In all controls and DCM patients, rotation was clockwise at the basal level and counterclockwise at the apical level. In contrast, in all NCCM patients the LV base and apex rotated in the same direction. Conclusions: These findings suggest that 'LV solid body rotation', with near absent LV twist, may be a new sensitive and specific, objective and quantitative, functional diagnostic criterion for NCCM.

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Section: Discussionmentioning

confidence: 37%

Left ventricular solid body rotation in non‐compaction cardiomyopathy: A potential new objective and quantitative functional diagnostic criterion?

Dalen

Çalışkan

Soliman

et al. 2008

European J of Heart Fail

116

View full text Add to dashboard Cite

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“…DTI possesses an intrinsic advantage in that it can directly detect myocardial velocity continuously through several cardiac cycles with high temporal resolution. 26 The current method, therefore, provides not only peak rotation and torsion but also the profile curve (the angular velocity and angular displacement over time) during systole and subsequent early diastole, something that the tagged MRI protocol used in this study cannot achieve because of fading of the tagging after 400 ms. 15,20 This later limitation of MRI could be overcome by retagging at end systole or steady-state free precession with myocardial tagging, 35 which can analyze LV deformation during the diastolic phase. The method used in this study was optimized for assessment of systolic function and early diastole.…”

Section: Advantage Of the Current Dti Methods For LV Torsion Assessmentmentioning

confidence: 99%

“…14 -17,32 MRI LV torsion measurement has been reported in patients with hypertrophic cardiomyopathy, 33 has revealed diastolic dysfunction in aortic stenosis due to delayed diastolic untwisting, 18,19 and has demonstrated persistent abnormal torsion after partial ventriculectomy. 20 …”

Section: Prior Pathophysiological Studies By Mri Of LV Torsionmentioning

confidence: 99%

Assessment of Left Ventricular Torsional Deformation by Doppler Tissue Imaging

et al. 2005

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Background-Left ventricular (LV) torsional deformation is a sensitive index for LV performance but difficult to measure.The present study tested the accuracy of a novel method that uses Doppler tissue imaging (DTI) for quantifying LV torsion in humans with tagged magnetic resonance imaging (MRI) as a reference. Methods and Results-Twenty patients underwent DTI and tagged MRI studies. Images of the LV were acquired at apical and basal short-axis levels to assess LV torsion. We calculated LV rotation by integrating the rotational velocity, determined from DTI velocities of the septal and lateral regions, and correcting for the LV radius over time. LV torsion was defined as the difference in LV rotation between the 2 levels. DTI rotational and torsional profiles throughout systole and diastole were compared with those by tagged MRI at isochronal points.

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“…[3][4][5][6][7] Tagged MRI has also been introduced to noninvasively assess LV torsion in various cardiac diseases by measuring LV myocardial deformation using labeling of specific ventricular regions. [8][9][10][11] However, implantation of myocardial markers occurs in a limited number of patients undergoing cardiac surgery or in experimental models, and the influence of the surgery should not be ignored. Both fluoroscopic and MRI analyses require special equipment for image acquisition, the frame rates are also limited, and these methods are time-consuming.…”

Section: Evaluation Of LV Torsionmentioning

confidence: 99%

Augmentation of Left Ventricular Apical Endocardial Rotation With Inotropic Stimulation Contributes to Increased Left Ventricular Torsion and Radial Strain in Normal Subjects Quantitative Assessment Utilizing a Novel Automated Tissue Tracking Technique

Akagawa

Murata

Tanaka

et al. 2007

Circ J

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he left ventricular (LV) myocardium consists of obliquely oriented muscle fibers that vary from a right-handed helix at the endocardium (Endo) to a left-handed helix at the epicardium (Epi), with most myofibers in approximately circumferential orientation. 1 This 3-dimensional myocardial structure results in rotation of the LV apex with respect to the base, which accompanies contraction and relaxation, and this LV rotational deformation is thought to generate LV torsion while also equalizing fiber stress and sarcomere length across the LV wall. 2 Many methods have been used to describe and quantify LV torsion, including cineangiography with radioopaque markers, 3-7 magnetic resonance imaging (MRI) 8-11 and 2-Circulation Journal Vol.71, May 2007 dimensional (2D) echocardiography. [12][13][14] The cineangiography technique requires implantation at the time of cardiac operation, thus limiting the population available for the study of LV torsion to patients with significant cardiac disease. MRI using myocardial tagging remains expensive and its temporal resolution is not sufficient to assess the time course of LV torsion in detail. 2D echocardiography is limited to measuring the rotation of a small number of identifiable structures such as the papillary muscles.We have developed a 2D echocardiographic tissue tracking system (2DTT) for tracking the locus of the LV myocardium to calculate myocardial strain without Doppler angle dependency. [15][16][17] The technique is based on a patternmatching algorithm, which enables tracking of selected points automatically during the whole cardiac cycle using digital image files.Using 2DTT, we tried to assess LV rotational deformation by calculating the rotation angles between the apex and base of the LV. 18-20 LV torsion of the Endo has been previously reported to be greater than that of the Epi according to tagged MRI analyses, [8][9][10] which suggests that shear occurs between the Endo and Epi (circumferentialradial shear) and this may play an important role in systolic Circ J 2007; 71: 661 -668 (Received December 4, 2006; revised manuscript received January 17, 2007; accepted January 29, 2007 Background The difference in the left ventricular (LV) torsion of the endo-and epicardium (Endo, Epi) with inotropic stimulation and its relation to radial strain (RS) remain unclear. Methods and Results LV basal and apical short-axis images were recorded in 13 normal subjects at rest and during dobutamine infusion (5, 10 g·kg -1 ·min -1 ). A total of 8 points (anterior, lateral, posterior and septum in both Endo and Epi) were manually placed by 2-dimensional tissue tracking technique and the movement of these points during a cardiac cycle was tracked, after which the rotation angles and RS were calculated. LV torsion was defined as the net difference between the basal and apical rotations. In the LV apex, Endo-rotation increased (7.8±2.7 to 14.1±4.6 degrees, p<0.01), whereas Epi-rotation was unchanged, with dobutamine. The apical Endorotation was significantly greater than the Ep...

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Persistent abnormal left ventricular systolic torsion in dilated cardiomyopathy after partial left ventriculectomy

Cited by 67 publications

References 30 publications

Left ventricular solid body rotation in non‐compaction cardiomyopathy: A potential new objective and quantitative functional diagnostic criterion?

Left ventricular solid body rotation in non‐compaction cardiomyopathy: A potential new objective and quantitative functional diagnostic criterion?

Assessment of Left Ventricular Torsional Deformation by Doppler Tissue Imaging

Augmentation of Left Ventricular Apical Endocardial Rotation With Inotropic Stimulation Contributes to Increased Left Ventricular Torsion and Radial Strain in Normal Subjects Quantitative Assessment Utilizing a Novel Automated Tissue Tracking Technique

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