Perseverative Writing Errors in a Patient with Alzheimer's Disease

Neils-Strunjaš, Jean; Shuren, Jeffrey; Roeltgen, David P.; Brown, Candace

doi:10.1006/brln.1997.1935

Cited by 31 publications

(19 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nonlinguistic errors of writing in AD were confined to letter formation in previous studies on alphabetic writings [28,[33][34][35][36][37], although we found stroke addition and omission as nonlinguistic errors in this study. However, among the nonlinguistic errors, graphemic misposition errors (Fig.…”

Section: Discussioncontrasting

confidence: 92%

Dysgraphia in Korean patients with Alzheimer's disease as a manifestation of bilateral hemispheric dysfunction

Yoon

Kim

Seo

et al. 2012

Journal of the Neurological Sciences

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 92%

Dysgraphia in Korean patients with Alzheimer's disease as a manifestation of bilateral hemispheric dysfunction

Yoon

Kim

Seo

et al. 2012

Journal of the Neurological Sciences

View full text Add to dashboard Cite

“…For example, patients with schizophrenia have diminished levels of ACC activity in response to errors (Kerns et al, 2005;Mathalon et al, 2002), with the level of dysfunction relating to the severity of disorganization symptoms (ie, formal thought disorder, inappropriate affect, and bizarre behavior) (Bates et al, 2002;Berman et al, 1997;Frith and Done, 1989;Liddle et al, 1992). Alzheimer's disease has also been associated with a progressive deterioration in error awareness (Cahn et al, 1997;Neils-Strunjas et al, 1998) and the neural response to errors (Mathalon et al, 2003).…”

Section: Post-error Adaptationmentioning

confidence: 99%

Post-Error Behavior in Active Cocaine Users: Poor Awareness of Errors in the Presence of Intact Performance Adjustments

Hester

Simões‐Franklin

Garavan

2007

Neuropsychopharmacol

108

View full text Add to dashboard Cite

Active cocaine abusers have a diminished neural response to errors, particularly in the anterior cingulate cortex thought critical to error processing. The inability to detect, or adjust performance following errors has been linked to clinical symptoms including the loss of insight and perseverative behavior. We investigated the cognitive implications of this diminished error-related activity, using response inhibition tasks that required error awareness and performance adaptation. Twenty-one active cocaine users (six female subjects, mean age ¼ 40.3) and 22 non-drug using adults (six female subjects, mean ¼ 39.9) participated. The results indicated that cocaine users consistently demonstrated poorer inhibitory control, a deficit accompanied by reduced awareness of errors. Adaptation of post-error reaction times did not differ between groups, although a different measure of adaptive behavior: exerting inhibitory control on the trial immediately after failing to inhibit, was significantly poorer in the cocaine using sample. In summary, cocaine users demonstrated a diminished capacity for monitoring their behavior, but were able to perform post-error adjustment to processes not already suffering an underlying deficit. These difficulties are consistent with previous reports of cocaine-related hypoactivity in the neural system underlying cognitive control, and highlight the potential for cognitive dysfunction to manifest as behavioral deficits that likely contribute to the maintenance of drug dependence.

show abstract

“…These findings become more obvious during the progress of the disease and in later stages the handwriting is no longer legible. In the latest stage, the patient is unable to write (13)(14)(15)(16)(17)(18).…”

Section: Introductionmentioning

confidence: 99%

Changes in Handwriting due to Alzheimer’s Disease a Case Report

Birincioğlu

Uzun²,

Alkan

et al. 2016

Bull Leg Med

View full text Add to dashboard Cite

Handwriting and signature comparisons are frequently performed in forensic investigations of documents. Mistakes in conclusion might be due to lack of sufficient documentation and information. Many factors can affect handwriting and signature. These factors are divided into two groups: dependent or independent of the individual at the time the handwriting or signature is made. Therefore, the situations leading to differences between individuals and in the individual's own handwriting and signature should be determined. Currently, average life expectancy and quality have increased due to the developments in health services. Thus, an increasing number of elderly people are engaged in an active daily life and trade. Alzheimer's Disease (AD) can develop in the elderly; this is a condition that could alter handwriting and signature considerably over time.In forensic document examination, comparing the document in question containing handwriting or signature with the original documents prepared before the document in question was prepared is important. However, if alterations have developed secondary to a disease, the documents prepared before and after the disease affected the individual should be assessed together.Likewise, in the present case, the examiners making comparisons using handwriting and signatures from different periods reached entirely different conclusions.The case is a bill prepared in 1994. The payee of the bill is a male born in 1925 and diagnosed with AD shortly before his death in 1998. The indebted person in the bill is the payee's spouse. For the assessment of handwriting and signature, the first endorsement consisting of the handwritten name and signature was used. Several expert reports regarding the same document had been commissioned; these reached different views. The document was sent to The Council of Forensic Medicine to assess the identification and the previous reports. After re-evaluation, the handwriting was declared to belong to the payee.In this study, the reason that the experts delivered opposing opinions on the identification of a document handwritten by a person with AD after being referred to court was investigated.Based on the judicial file, the document examiners did not have the opportunity to evaluate all factors affecting the handwriting or signature of the individual, and an adequate number of handwriting and signature examples were not collected for comparison. Consequently, the examiners reached different opinions. Thus, the above-mentioned factors are necessary to derive a satisfactory and accurate opinion regarding the identification of handwriting or signature.Keywords: Forensic sciences; Handwriting; Signature; Alzheimer's Disease. ÖzetPek çok faktör el yazısı ve imzalarda değişikliğe sebep olmaktadır. Bu faktörler, yazı ve imzanın oluşturulduğu andaki çevresel koşullar ve kişiye bağlı değişiklikler olarak iki grupta toplanır. Bu nedenle, el yazısı ve imzalarda kişiden kişiye oluşan farklılaşmalar ile kişinin kendisinde değişikliğe neden olan durumların adl...

show abstract

Perseverative Writing Errors in a Patient with Alzheimer's Disease

Cited by 31 publications

References 34 publications

Dysgraphia in Korean patients with Alzheimer's disease as a manifestation of bilateral hemispheric dysfunction

Dysgraphia in Korean patients with Alzheimer's disease as a manifestation of bilateral hemispheric dysfunction

Post-Error Behavior in Active Cocaine Users: Poor Awareness of Errors in the Presence of Intact Performance Adjustments

Changes in Handwriting due to Alzheimer’s Disease a Case Report

Contact Info

Product

Resources

About