Peroxy Pyruvic Acid-Containing Topical Anti-Infective: A Potential Candidate for a Wound Instillation Solution

Neas, Edwin D.; Dunn, Julie; Silva, Evelyn Dimaano; Chambers, Ali; Luckasen, Gary J.; Jaskowiak, Adam

doi:10.1089/wound.2015.0682

Cited by 2 publications

(1 citation statement)

References 48 publications

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“…In addition, other antimicrobial solutions are available, including iodine solution, peroxyacid solution, chlorhexidine solution, and oxygen loaded solution, which are used for NPWTi, and reports have noted their therapeutic effects. [19][20][21][22]…”

Section: Antimicrobial Solutionsmentioning

confidence: 99%

Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds

Wen

et al. 2022

International Wound Journal

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Negative pressure wound therapy with instillation (NPWTi) has the dual function of negative pressure sealing drainage and irrigation, which overcomes the disadvantages of NPWT, such as tube obstruction, inability to apply topical medicine, and poor anti-infection ability. NPWTi has been researched extensively and widely used in various types of wounds, and certain effects have been achieved. A series of parameters for NPWTi have not been unified at present, including the flushing fluid option, flushing mode, and treatment period. This paper reviews the research progress of these parameters for NPWTi and their application in the treatment of orthopaedic wounds.instillation, negative pressure wound therapy, orthopaedic wounds, treatment parameters Key Messages• NPWTi has the dual function of negative pressure sealing drainage and irrigation • setting of treatment parameters for NPWTi has not been unified yet: further research studies are required • although there are multiple choices of instillation solutions, normal saline is recommended as the first choice; the recommended setting is the intermittent instillation mode and À125 to 150 mmHg, the duration time depends on the type of wound • NPWTi has been widely used in all kinds of wounds in orthopaedics, such as acute or chronic infected wounds, osteomyelitis, soft tissue injuries, and surgical wound management

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Section: Antimicrobial Solutionsmentioning

confidence: 99%

Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds

Wen

et al. 2022

International Wound Journal

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Consensus on the application of negative pressure wound therapy of diabetic foot wounds

Ji¹,

Liu²,

Huang³

et al. 2021

Burns &Amp; Trauma

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Because China is becoming an aging society, the incidence of diabetes and diabetic foot have been increasing. Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates. Negative pressure wound therapy (NPWT) is one of the most effective techniques for the treatment of diabetic foot wounds and great progress, both in terms of research and its clinical application, has been made in the last 20 years of its development. However, due to the complex pathogenesis and management of diabetic foot, irregular application of NPWT often leads to complications, such as infection, bleeding and necrosis, that seriously affect its treatment outcomes. In 2020, under the leadership of Burns, Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association, the writing group for ‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’ was established with the participation of scholars from the specialized areas of burns, endocrinology, vascular surgery, orthopedics and wound repair. Drawing on evidence-based practice suggested by the latest clinical research, this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot. The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot.

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Peroxy Pyruvic Acid-Containing Topical Anti-Infective: A Potential Candidate for a Wound Instillation Solution

Cited by 2 publications

References 48 publications

Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds

Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds

Consensus on the application of negative pressure wound therapy of diabetic foot wounds

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