Perovskite nickelates as bio-electronic interfaces

Abstract

Functional interfaces between electronics and biological matter are essential to diverse fields including health sciences and bio-engineering. Here, we report the discovery of spontaneous (no external energy input) hydrogen transfer from biological glucose reactions into SmNiO 3 , an archetypal perovskite quantum material. The enzymatic oxidation of glucose is monitored down to ~5 × 10 −16 M concentration via hydrogen transfer to the nickelate lattice. The hydrogen atoms donate electrons to the Ni d orbital and induce electron localization through strong electron correlations. By enzyme specific modification, spontaneous transfer of hydrogen from the neurotransmitter dopamine can be monitored in physiological media. We then directly interface an acute mouse brain slice onto the nickelate devices and demonstrate measurement of neurotransmitter release upon electrical stimulation of the striatum region. These results open up avenues for use of emergent physics present in quantum materials in trace detection and conveyance of bio-matter, bio-chemical sciences, and brain-machine interfaces.

Perovskite neural trees

“…We added a small monoclinic distortion (β ≈ 90.75) and allowed the cell and ionic positions to relax until we met the electronic and ionic convergence criterion. The H SmNiO 3 structures were adopted by AIMD simulations from literature 50,51 . To compute the barrier associated with H migration on SmNiO 3 [110] slab, we used climbing image nudged-elastic band method.…”

Quantum Sensing for Energy Applications: Review and Perspective

“…[ 98,144 ] Despite their relatively weak emission, [ 98 ] the long nuclear spin relaxation and coherence times of rare earth ions, [ 98 ] coupled with relatively facile synthetic strategies, [ 144 ] have spurred significant interest in developing rare earth‐based quantum materials. While not extensively evaluated for sensing applications, a range of rare earth‐ion doped solids have been produced, including europium and erbium‐doped yttrium oxide, [ 145 ] europium‐doped yttrium silicate (Y 2 SiO 5 ), [ 146 ] samarium nickelate, [ 147,148 ] cerium‐ [ 149 ] and praseodymium [ 150,151 ] ‐doped yttrium aluminum garnet (YAG), thulium‐doped lithium niobite, [ 152 ] and others. [ 144 ]…”

Pressure Induced Unstable Electronic States upon Correlated Nickelates Metastable Perovskites as Batch Synthesized via Heterogeneous Nucleation

“…[ 1–3 ] It effectively broadens the adjustability in the electronic structures and transportation properties for semiconductors, [ 4–6 ] shedding a light on the discovery of emerging new materials functionalities that does not exist in conventional equilibrium condensed matters. As one of the most representative metastable quantum materials, the perovskite structured rare‐earth nickelates ( Re NiO 3 ) exhibit complicated multiple electronic states that are ultrasensitive to external stimulus, such as temperature, [ 7–11 ] electronic polarization, [ 12 ] chemical [ 13–16 ] or electrochemical doping, [ 17–19 ] structural distortions, [ 20–26 ] etc. Triggering the electronic transitions among the multiple quantum states of Re NiO 3 or hydrogenated Re NiO 3 enriches new applications in electron correlated electronics, such as correlated logical devices, [ 12 ] neuron‐synapse quantum computing, [ 16 ] correlated proton conductors, [ 15 ] weak current ocean sensor, [ 17 ] and biosensors.…”

“…Triggering the electronic transitions among the multiple quantum states of Re NiO 3 or hydrogenated Re NiO 3 enriches new applications in electron correlated electronics, such as correlated logical devices, [ 12 ] neuron‐synapse quantum computing, [ 16 ] correlated proton conductors, [ 15 ] weak current ocean sensor, [ 17 ] and biosensors. [ 18 ]…”