Peroral endoscopy and laryngeal surgery

Jackson, Chevalier

doi:10.1288/00005537-191608000-00009

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…[51][52][53][54][55] This omnitemporal impact is unlike the influence of the majority of infectious airway diseases that dominated laryngological literature in the 19th century and unlike epithelial cancer, which has been a centerpiece of 20th-century academic investigation. [51][52][53][54][55] This omnitemporal impact is unlike the influence of the majority of infectious airway diseases that dominated laryngological literature in the 19th century and unlike epithelial cancer, which has been a centerpiece of 20th-century academic investigation.…”

Section: Discussionmentioning

confidence: 99%

Microlaryngoscopic and Office-Based Injection of Bevacizumab (Avastin) to Enhance 532-nm Pulsed KTP Laser Treatment of Glottal Papillomatosis

Zeitels¹,

Lopez‐Guerra²,

Burns³

et al. 2009

Ann Otol Rhinol Laryngol

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Objectives: Photoangiolytic lasers effectively treat glottal papillomatosis, but do not reliably prevent recurrence. Therefore, sublesional injections of the antiangiogenic agent bevacizumab (Avastin) were given to assess the effect on disease recurrence and phonatory function. Methods: A retrospective investigation was done in a pilot group of 10 adult patients with bilateral glottal papillomatosis who had prior angiolytic laser treatment with established patterns of recurrence. The patients underwent 5 bevacizumab injections (5 to 10 mg) into the diseased vocal folds along with 532-nm pulsed KTP laser photoangiolysis treatments 4 to 6 weeks apart. Their disease resolution was compared to findings from prior laser treatment alone, and objective measures of vocal function (acoustic, aerodynamic, Voice-Related Quality of Life survey) were obtained. Results: All 10 patients had a greater than 90% reduction in recurrence. Four of the 10 had resolution. Four of the 10 have limited recurrent or persistent disease, receive injections of bevacizumab at 8-to 12-week intervals, and have not required laser treatment. Two of the 10 have ongoing periodic office-based KTP laser treatment along with bevacizumab injections. No patient has required microlaryngeal surgery with general anesthesia, and all 10 have had substantial improvement in vocal function. Conclusions: This pilot investigation provides preliminary evidence that bevacizumab injections enhance photoangiolytic laser treatment of glottal papillomatosis while enhancing phonatory function. Coupling an antiangiogenesis agent with pulsed KTP laser photoangiolysis is conceptually promising, since the mechanisms of action are complementary.

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Section: Discussionmentioning

confidence: 99%

Microlaryngoscopic and Office-Based Injection of Bevacizumab (Avastin) to Enhance 532-nm Pulsed KTP Laser Treatment of Glottal Papillomatosis

Zeitels¹,

Lopez‐Guerra²,

Burns³

et al. 2009

Ann Otol Rhinol Laryngol

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“…Support for both approaches has been published in the literature from the early 20th century through to modern texts. 7,8,11,12 To the best of our knowledge our study is the first video-based evaluation of laryngoscopy that has evaluated the effect of approach on outcome.…”

Section: Right-sided N=41mentioning

confidence: 99%

Using Video‐recorded Laryngoscopy to Evaluate Laryngoscopic Blade Approach and Adverse Events in Children

Green-Hopkins

Werner

Monuteaux

et al. 2015

Academic Emergency Medicine

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Objectives: Using recordings of endotracheal intubation attempts obtained with a video-enabled laryngoscope with Miller and Macintosh blades, the authors sought to evaluate the association between laryngoscopic approach (right-sided vs. midline) and intubation success, as well as adverse event rates in the pediatric emergency department (ED).Methods: This was a retrospective cohort study of children younger than 21 years who underwent endotracheal intubation with a C-MAC video laryngoscope in a tertiary care ED between August 2009 and May 2013. The primary outcome was successful endotracheal intubation on the first attempt. The secondary outcomes included time to intubation, video-recorded adverse events (oropharyngeal mucosal injury and aspiration), and physiologic adverse events. Multivariate regression models were used to determine the relationship between laryngoscope blade position and outcome measures adjusted for patient and provider factors.Results: The cohort consisted of complete video recordings for 105 of 143 (73%) patient encounters with intubations. The first-pass success rate did not significantly differ based on laryngoscopic approach (adjusted odds ratio [aOR] = 0.76, 95% confidence interval [CI] = 0.29 to 2.0). Among patients successfully intubated on the first attempt, the median time to intubation was longer for the right-sided approach compared to the midline approach (42 seconds vs. 31.5 seconds; p < 0.05). The odds of mucosal injury and aspiration were higher among patients intubated using a right-sided approach compared to a midline approach (aOR = 4.1, 95% CI = 1.2 to 14.5; aOR = 7.7, 95% CI = 1.5 to 39.5, respectively). Rates of physiologic adverse events did not differ based on approach.Conclusions: First-pass success rate did not differ based upon laryngoscopic approach type; however, a right-sided approach was associated with a longer time to intubation, as well as higher rates of mucosal injury and aspiration among patients undergoing video-enabled intubation in a pediatric ED.

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“…Dysphagia because of spasm of upper esophageal sphincter was first described in 1915 by Jackson [2]; this condition was seen in adults in whom it was usually secondary to a neurologic disease. The first report of cricopharyngeal achalasia in infancy was by Utian and Thomas [3] in 1967.…”

mentioning

confidence: 99%