Permselectivity of Silk Fibroin Hydrogels for Advanced Drug Delivery Neurotherapies
Rocío Fernández-Serra,
Amira Lekouaghet,
Lorena Peracho
et al.
Abstract:A promising trend in tissue engineering is using biomaterials to improve the control of drug concentration in targeted tissue. These vehicular systems are of specific interest when the required treatment time window is higher than the stability of therapeutic molecules in the body. Herein, the capacity of silk fibroin hydrogels to release different molecules and drugs in a sustained manner was evaluated. We found that a biomaterial format, obtained by an entirely aqueous-based process, could release molecules … Show more
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