Permeability of latex and thermoplastic elastomer gloves to the bacteriophage φX174

Hamann, Carsten R.; Nelson, Jerry R.

doi:10.1016/0196-6553(93)90385-h

Cited by 22 publications

(4 citation statements)

References 21 publications

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“…Gloves are worn to protect hands from contamination with organic matter and microorganisms, and also to reduce the risks of transmission of microorganism to both patients and staff. However, there is good evidence that the gloves used for clinical practice leak when they appear apparently un‐damaged and gloves made from NRL have been shown to perform better than vinyl gloves when laboratory tested for leakage 5,6 . In the mid 1980s there was increased demand for NRL gloves, some were imported from manufacturers inexperienced with the production of latex products for healthcare use and not subject to quality assurance procedures appropriate for medical equipment.…”

Section: Introductionmentioning

confidence: 99%

Contact dermatoses in healthcare workers: reduction in type I latex allergy in a UK centre

Clayton

Wilkinson

2005

Clin Exp Dermatol

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Natural rubber latex (NRL) allergy has been recognized as a public health concern. NRL allergy frequently occurs in healthcare professionals. In this retrospective study we report the changing frequency of Type I NRL allergy amongst healthcare workers suffering from hand dermatitis referred to our department between 1996 and 2003. We identified 224 healthcare workers from the patch test database with a diagnosis of hand dermatitis who had undergone NRL skin prick testing (SPT). We report the SPT results, patch test results and diagnoses for each individual. The percentage of positive SPT to NRL in healthcare workers decreased from 62% in 1996 to 10% in 2003. Type IV allergy to fragrance mix (13%) was the most frequent cause of allergic contact dermatitis. Thiuram mix (8%) and carba mix (4%) were the most frequent indicators of type IV allergy to chemicals in rubber gloves. Fragrance allergy was the most frequent type IV allergen found in healthcare workers with hand dermatitis. We conclude that hand care preparations free from fragrance allergens should be available in all areas of clinical work.

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Section: Introductionmentioning

confidence: 99%

Contact dermatoses in healthcare workers: reduction in type I latex allergy in a UK centre

Clayton

Wilkinson

2005

Clin Exp Dermatol

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“…However, hydrogels' promise and potential in these new applications have been significantly hampered by their low mechanical robustness and permeability to various molecules . For example, the strength and fracture toughness of common hydrogels are usually much lower than the corresponding elastomers (e.g., silicone rubbers and latex) used for the abovementioned applications; and water‐soluble molecules and viruses may diffuse through hydrogels but not elastomers . Despite recent success in developing hydrogels with extraordinary mechanical properties, the design of impermeable robust hydrogels has remained a challenge in the field.…”

Section: Coefficient Of Friction (Cof) For Different Surfaces As a Fumentioning

confidence: 99%

“…Nevertheless, the laminates possess a set of properties and capabilities unachievable in existing hydrogels: (a) the laminates have high water content, slippery surfaces, and can be functionalized with biomolecules in the same fashion as common hydrogels . (b) The laminates are robust, highly stretchable, and impermeable to molecules of various types and sizes across the structure, similar to bulk elastomer sheets . (c) The modulus of the laminate (along in‐plane directions) can be tuned by varying the types of elastomer, type and composition of the hydrogel layers, and the thicknesses of the different layers.…”

Section: Coefficient Of Friction (Cof) For Different Surfaces As a Fumentioning

confidence: 99%

Impermeable Robust Hydrogels via Hybrid Lamination

Parada

Yuk

Liu

et al. 2017

Adv Healthcare Materials

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Hydrogels have been proposed for sensing, drug delivery, and soft robotics applications, yet most of these materials suffer from low mechanical robustness and high permeability to small molecules, limiting their widespread use. This study reports a general strategy and versatile method to fabricate robust, highly stretchable, and impermeable hydrogel laminates via hybrid lamination of an elastomer layer bonded between hydrogel layers. By controlling the layers' composition and thickness, it is possible to tune the stiffness of the impermeable hydrogels without sacrificing the stretchability. These hydrogel laminates exhibit ultralow surface coefficients of friction and, unlike common single-material hydrogels, do not allow diffusion of various molecules across the structure due to the presence of the elastomer layer. This feature is then used to release different model drugs and, in a subsequent experiment, to sense different pH conditions on the two sides of the hydrogel laminate. A potential healthcare application is shown using the presented method to coat medical devices (catheter, tubing, and condom) with hydrogel, to allow for drug release and sensing of environmental conditions for gastrointestinal or urinary tract.

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“…Research studies comparing various properties of nonlatex materials to those of latex have been published and are readily found in the literature. For example, multiple authors have studied leakage of both latex and nonlatex gloves after clinical use,1–5 simulated use,6–10 or directly out of the box 11–13. Physical properties such as puncture resistance, tensile strength, stiffness, and ease of donning for various glove materials have been studied 2, 7, 9, 14, 15.…”

Section: Introductionmentioning

confidence: 99%

Abrasion resistance of medical glove materials

et al. 2003

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Due to the increasing demand for nonlatex medical gloves in the health-care community, there is a need to assess the durability of alternative glove materials. This study examines durability characteristics of various glove materials by abrasion resistance testing. Natural rubber latex (latex), polyvinyl chloride (vinyl), acrylonitrile butadiene (nitrile), polychloroprene (neoprene), and a styrene-ethylene/butylene-styrene block copolymer (SEBS) were tested. All test specimens, with the exception of the vinyl, were obtained from surgical gloves. Unaged out-of-the-box specimens as well as those subjected to various degrees of artificial aging were included in the study. After the abrasion sequence, the barrier integrity of the material was assessed through the use of a static leak test. Other traditional tests performed on these materials were viral penetration to validate the abrasion data and tear testing for comparative purposes. The results indicate that specific glove-material performance is dependent upon the particular test under consideration. Most notably, abrasion, even in controlled nonsevere conditions, may compromise to varying degrees the barrier integrity of latex, vinyl, SEBS, nitrile, and neoprene glove materials. However, as evidenced by the results of testing three brands of neoprene gloves, the abrasion resistance of any one glove material may be significantly affected by variations in production processes.

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Permeability of latex and thermoplastic elastomer gloves to the bacteriophage φX174

Cited by 22 publications

References 21 publications

Contact dermatoses in healthcare workers: reduction in type I latex allergy in a UK centre

Contact dermatoses in healthcare workers: reduction in type I latex allergy in a UK centre

Impermeable Robust Hydrogels via Hybrid Lamination

Abrasion resistance of medical glove materials

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