1993
DOI: 10.1016/s0272-6386(12)80391-x
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Permanent Vascular Access: A Nephrologist's View

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Cited by 278 publications
(150 citation statements)
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References 95 publications
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“…However, stenosis and thrombosis substantially contribute to the difficulty in maintaining the patency of AVF. Stenoses account for over 80% of AVF thromboses; thromboses are responsible for 80% to 85% of AVF failures (1). Stenosis of vascular access is histologically characterized by intimal hyperplasia, which results from the initial proliferation of vascular smooth muscle cells (VSMCs) and the subsequent migration of VSMCs from the media to the intima, and exuberant synthesis of extracellular matrix, which leads to further intimal expansion (2).…”
mentioning
confidence: 99%
“…However, stenosis and thrombosis substantially contribute to the difficulty in maintaining the patency of AVF. Stenoses account for over 80% of AVF thromboses; thromboses are responsible for 80% to 85% of AVF failures (1). Stenosis of vascular access is histologically characterized by intimal hyperplasia, which results from the initial proliferation of vascular smooth muscle cells (VSMCs) and the subsequent migration of VSMCs from the media to the intima, and exuberant synthesis of extracellular matrix, which leads to further intimal expansion (2).…”
mentioning
confidence: 99%
“…Malfunction of vascular access usually presents with inadequate blood flow because of stenosis or thrombosis of the venous outflow tract (2). Approximately 80 to 85% of AV access failures arise from AV access thromboses, more than 80% of which result from AVF stenoses (3). An access flow (Qa), Ͻ500 ml/min was associated with an increased risk for access failure and predictive of poorer unassisted patency of native AVF (4).…”
mentioning
confidence: 99%
“…Recent data indicate that the majority of patients on hemodialysis in the United States have prosthetic graft fistulas. The most frequent complications of prosthetic graft fistulas are thrombosis and stenosis 135. Endovascular interventions have replaced surgical repair as the primary treatment of the failing or thrombosed vascular access.…”
Section: Discussionmentioning
confidence: 99%