Permanent pacing for recurrent vasovagal syncope: New answers or just more questions?

Aksu, Tolga; Mandrola, John; Raj, Satish R.

doi:10.1016/j.jelectrocard.2021.01.010

Cited by 6 publications

(3 citation statements)

References 17 publications

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“…However, a consensus on the optimal mapping method, ablation foci, or procedural endpoints has not been reached yet. 10,16,17 Recent ESC guidelines have cited CNA as a potential method for the treatment of VVS, but did not provide any class of recommendations. 1 For this, well-designed, double-blind, multicenter, sham-controlled randomized clinical trials are needed.…”

Section: Discussionmentioning

confidence: 99%

“…There have been many published reports of CNA in recent years, all reporting low incidences of syncope recurrence following CNA. However, a consensus on the optimal mapping method, ablation foci, or procedural endpoints has not been reached yet 10,16,17 . Recent ESC guidelines have cited CNA as a potential method for the treatment of VVS, but did not provide any class of recommendations 1 .…”

Section: Discussionmentioning

confidence: 99%

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Cardioneuroablation for treatment of carotid sinus syndrome secondary to oropharyngeal squamous cell cancer

Bozyel

Güler

Çelik

et al. 2023

Cardiovasc electrophysiol

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Head and neck tumors can rarely cause carotid sinus syndrome and this often resolves by surgical intervention or palliative chemoradiotherapy. If these modalities are not an option or are ineffective, the most preferred treatment is permanent pacemaker therapy. Here, we present the first case of cardioneuroablation treatment performed in patient with oropharyngeal squamous cell cancer who developed recurrent asystole and syncope attacks due to compression of the carotid sinus on neck movement.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cardioneuroablation for treatment of carotid sinus syndrome secondary to oropharyngeal squamous cell cancer

Bozyel

Güler

Çelik

et al. 2023

Cardiovasc electrophysiol

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“…Cardiac pacing has been investigated for decades as a potential therapeutic option with controversial results [2]. Identifying suitable candidates for pacing and avoiding futile implantations have always been the main concern [3].…”

Section: Introductionmentioning

confidence: 99%

Heart rate distribution in paced and non-paced patients with severe recurrent reflex syncope and tilt-induced asystole: Findings from the BIOSync CLS study

Russo

Anguera

Lange

et al. 2021

International Journal of Cardiology

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Background: Undiagnosed sinus or atrioventricular node dysfunction may bias estimation of the real efficacy of cardiac pacing in preventing vasovagal reflex syncope. We assessed this hypothesis in the BIOSync CLS trial which showed that dual-chamber pacing with closed loop stimulation (CLS) remarkably reduced recurrences of syncope. Methods and results: In the study patients aged 40 years or older with ≥2 episodes of loss of consciousness in the last year and an asystolic response to Tilt-Table test were randomized to pacing ON (DDD-CLS mode) or pacing OFF (ODO mode). We utilized the available pacemaker diagnostic data in a total of 103 patients (52 pacing ON, 51 pacing OFF) to generate cumulative distribution charts for heart rate (HR) and percentage of pacing. At 12 months, we did not find evidence of suspected sinus or atrioventricular node dysfunction. Beats were similarly distributed between groups (p = 0.96), with an average HR of 76 ± 8 bpm (pacing ON) versus 77 ± 7 bpm (pacing OFF). In the active group, the median percentage of atrial and ventricular pacing was 47% and 0%, respectively. Intolerance to high pacing rates was reported in only one patient (1.6%) and was easily resolved by reprogramming the maximum CLS pacing rate. Conclusions: We did not find evidence of suspected sinus or atrioventricular node dysfunction in the BIOSync CLS patients. The benefit of pacing should be ascribed to pacing prevention of pure vasovagal episodes. CLS algorithm modulated pacing rates over a wide frequency range, consistently competing with sinus node.

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Cardioneuroablation for the Treatment of Vasovagal Syncope: Current Status and Impact on Quality of Life

Traykov,

Shalganov

2023

Curr Cardiol Rep

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Permanent pacing for recurrent vasovagal syncope: New answers or just more questions?

Cited by 6 publications

References 17 publications

Cardioneuroablation for treatment of carotid sinus syndrome secondary to oropharyngeal squamous cell cancer

Cardioneuroablation for treatment of carotid sinus syndrome secondary to oropharyngeal squamous cell cancer

Heart rate distribution in paced and non-paced patients with severe recurrent reflex syncope and tilt-induced asystole: Findings from the BIOSync CLS study

Cardioneuroablation for the Treatment of Vasovagal Syncope: Current Status and Impact on Quality of Life

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