Permanent Pacemaker Implantation Following Transcatheter Aortic Valve Replacement

Savino, Danielle; McCarthy, Fenton H.; Spragan, Danielle; Dibble, Taylor; Graves, Desmond; Dufendach, Keith; Giri, Jay; Szeto, Wilson Y.; Groeneveld, Peter W.; Herrmann, Howard C.; Bavaria, Joseph E.; Desai, Nimesh D.

doi:10.1016/j.jcin.2017.04.016

Cited by 2 publications

(3 citation statements)

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“…Despite the growing popularity of TAVR, the need for a permanent pacemaker (PPM) following the procedure represents a frequently encountered complication and often occurs following the development of atrioventricular (AV) conduction abnormalities . Rates of PPM implantation post‐TAVR range from 2% to 51%; however, the bulk of patients receive a PPM either during or within the acute period following the valve replacement …”

Section: Introductionmentioning

confidence: 99%

Incidence of arrhythmias and impact of permanent pacemaker implantation in hospitalizations with transcatheter aortic valve replacement

Doshi

Decter

Meraj

2018

Clinical Cardiology

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Section: Introductionmentioning

confidence: 99%

Incidence of arrhythmias and impact of permanent pacemaker implantation in hospitalizations with transcatheter aortic valve replacement

Doshi

Decter

Meraj

2018

Clinical Cardiology

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“…New cardiac conduction disorders and arrhythmias such as atrioventricular block, left bundle branch block (LBBB), or other conditions requiring a permanent pacemaker (PPM) are the most common problems associated with TAVI. 4 The risk of PPM implantation has been shown to vary depending on the device used for TAVI. Balloonexpandable devices have a lower PPM implantation rate.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of acute CORticosteroids on conduction defects after Transcatheter Aortic Valve Implantation: the CORTAVI study

Barone

Muscoli

Belli

et al. 2023

Journal of Cardiovascular Medicine

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Aims Conduction abnormalities, requiring a permanent pacemaker (PPM), are the most common electrical complications after transcatheter aortic valve implantation (TAVI). The exact mechanism for conduction system defects is not yet clear. The local inflammatory process and edema are thought to play a role in the development of electrical disorders. Corticosteroids are effective anti-inflammatory and antiedematous agents. We aim to investigate the potential protective effect of corticosteroids on conduction defects after TAVI. Methods This is a retrospective study of a single center. We analyzed 96 patients treated with TAVI. Thirty-two patients received oral prednisone 50 mg for 5 days after the procedure. This population was compared with the control group. All patients were followed up after 2 years. Results Of the 96 patients included, 32 (34%) were exposed to glucocorticoids after TAVI. No differences in age, preexisting right bundle branch block or left bundle branch block, or valve type were seen among patients exposed to glucocorticoids versus those who were unexposed. We observed no significant differences between the two groups in the overall frequency of new PPM implantations during hospitalization (12% vs. 17%, P = 0.76). The incidence of atrioventricular block (AVB) (STx 9% vs. non-STx 9%, P = 0.89), right bundle branch block (STx 6% vs. non-STx 11%, P = 0.71), and left bundle branch block (STx 34% vs. non-STx 31%, P = 0.9) was not significantly different between the STx and non-STx groups. At 2 years after TAVI, none of the patients had implanted PPM or had severe arrhythmias documented by 24-h Holter ECG or cardiac examination. Conclusion Oral prednisone treatment does not appear to significantly reduce the incidence of AVB requiring acute PPM implantation after TAVI.

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Permanent Pacemaker Implantation Following Transcatheter Aortic Valve Replacement

Cited by 2 publications

References 5 publications

Incidence of arrhythmias and impact of permanent pacemaker implantation in hospitalizations with transcatheter aortic valve replacement

Incidence of arrhythmias and impact of permanent pacemaker implantation in hospitalizations with transcatheter aortic valve replacement

Effect of acute CORticosteroids on conduction defects after Transcatheter Aortic Valve Implantation: the CORTAVI study

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