Permanent Injectable Polyacrylamide Hydrogel Dermal Filler for a Large Subcutaneous Defect Secondary to Lupus Panniculitis

Gupta, Khushboo; Bhari, Neetu; Verma, Kaushal K.; Gupta, Somesh

doi:10.1097/dss.0000000000000839

Cited by 9 publications

(13 citation statements)

References 4 publications

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“…Nonpermanent fillers, such as HA and poly-L-lactic acid (PLLA), have been successfully employed to treat atrophy linked to linear morphea, scleroderma, LE, and LE panniculitis (LEP) (Gupta, Bhari, Verma, & Gupta, 2017;Ponzo, Carruthers, & Humphrey, 2017;Thareja, Sadhwani, & Alan Fenske, 2015) Permanent fillers such as polymethylmethacrylate and polyacrylamide hydrogel have also yielded excellent results in scleroderma en coup de sabre and LEP-induced subcutaneous tissue atrophy (Franco, Serra, Lima, D'Acri, & Martins, 2016;Gupta et al, 2017).…”

Section: Fillersmentioning

confidence: 99%

“…Delayed gel induration is one of the principal complications of polyacrylamide filler use, resulting in significant concerns in CTDs (Gupta et al, 2017). However, there are no published case reports about this.…”

Section: Fillersmentioning

confidence: 99%

“…Nonpermanent fillers, such as HA and poly‐ l ‐lactic acid (PLLA), have been successfully employed to treat atrophy linked to linear morphea, scleroderma, LE, and LE panniculitis (LEP) (Gupta, Bhari, Verma, & Gupta, ; Ponzo, Carruthers, & Humphrey, ; Thareja, Sadhwani, & Alan Fenske, )…”

Section: Introductionmentioning

confidence: 99%

“…Permanent fillers such as polymethylmethacrylate and polyacrylamide hydrogel have also yielded excellent results in scleroderma en coup de sabre and LEP‐induced subcutaneous tissue atrophy (Franco, Serra, Lima, D'Acri, & Martins, ; Gupta et al, ). Delayed gel induration is one of the principal complications of polyacrylamide filler use, resulting in significant concerns in CTDs (Gupta et al, ). However, there are no published case reports about this.…”

Section: Introductionmentioning

confidence: 99%

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Cosmetical treatments of connective tissue disorders

Arıca

2019

Dermatologic Therapy

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Connective tissue disorders (CTDs) are chronic inflammatory conditions that can lead to scarring and disfiguration. Although conventional methods are often of little benefit in cutaneous manifestations, the use of cosmetic procedures is still controversial. Concerns have also been raised concerning cosmetic treatments in CTDs, and particularly regarding lasers and fillers, due to photosensitivity and potential reactivation. This article reviews the cosmetic treatment of various CTDs under three headings ‐ lasers, fillers, and botulinum toxin.

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Section: Fillersmentioning

confidence: 99%

Section: Fillersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Cosmetical treatments of connective tissue disorders

Arıca

2019

Dermatologic Therapy

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“…Polyacrylamide gel is used extensively in biochemistry, biotechnology, forensic science, genetics, microbiology, molecular biology and virology . It is also used for wastewater treatment, oil recovery, papermaking, dermal fillers, personal care products and for various biomedical applications . Commercial high molecular weight polyacrylamide is obtained from conventional radical polymerization .…”

Section: Figurementioning

confidence: 99%

Unprecedented Acid‐Promoted Polymerization and Gelation of Acrylamide: A Serendipitous Discovery

Chan

Goh

Dou

et al. 2018

Chemistry An Asian Journal

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Dilute acid polymerizes degassed, aqueous acrylamide with concomitant gelation, without the need for added free radical initiator or cross-linking agent. This reaction is accelerated by sonication or UV irradiation, but inhibited by adventitious oxygen or the addition of a free radical inhibitor, suggesting an acid-accelerated free radical process. The resulting hydrogels are thixotropic in nature and partially disrupted by the addition of chaotropic agents, indicating the importance of hydrogen bonding to the 3D network. This discovery was made while trying to prepare pectin-polyacrylamide hydrogels. We observed that pectin initiated the gelation of acrylamide, but only if the aqueous pectin samples had a pH lower than ca. 5.

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Lupus Erythematosus and Antiphospholipid Syndrome

Dutz,

Khosravi‐Hafshejani

2024

Rook's Textbook of Dermatology

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Lupus erythematosus is an autoimmune disease that commonly affects the skin, and may present with cutaneous only disease. This chapter reviews the forms of cutaneous lupus‐specific skin disease (discoid lupus, subacute cutaneous lupus, lupus tumidus and acute cutaneous lupus), their clinical features, pathogenesis and treatment. A review of systemic lupus erythematosus is also provided with a discussion of diagnosis, clinical features, cutaneous aspects and treatment, germane for the dermatologist. Clinical features of neonatal lupus erythematosus and the antiphospholipid antibody syndrome, more commonly seen in systemic lupus erythematosus kindreds, are also discussed.

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Permanent Injectable Polyacrylamide Hydrogel Dermal Filler for a Large Subcutaneous Defect Secondary to Lupus Panniculitis

Cited by 9 publications

References 4 publications

Cosmetical treatments of connective tissue disorders

Cosmetical treatments of connective tissue disorders

Unprecedented Acid‐Promoted Polymerization and Gelation of Acrylamide: A Serendipitous Discovery

Lupus Erythematosus and Antiphospholipid Syndrome

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