1996
DOI: 10.1089/end.1996.10.283
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Periurethral Injection of the Genitourinary Spheroidal Membrane

Abstract: Periurethral injection of bulking agents to cause coaptation of the urethral walls has long been used in the treatment of urinary incontinence. A new form of this treatment is the silicone Genitourinary Spheroidal Membrane (Genisphere), which is placed in the periurethral tissues with a special delivery tool. Among 39 women who received two or three Genispheres, 29 (77%) became dry or markedly improved with a significant increase in leak-point and proximal urethral closure pressures. Early sexual activity, a s… Show more

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Cited by 9 publications
(2 citation statements)
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“…When reading this article, many will remember the previous anti-incontinence device termed genitourinary spheroidal membranes which were placed approximately 20 years ago (1). The advantage of this contemporary device is the potential for less migration and the ability to postoperatively titrate.…”
mentioning
confidence: 99%
“…When reading this article, many will remember the previous anti-incontinence device termed genitourinary spheroidal membranes which were placed approximately 20 years ago (1). The advantage of this contemporary device is the potential for less migration and the ability to postoperatively titrate.…”
mentioning
confidence: 99%
“…An interesting technology, which is not overly dissimilar to the genitourinary spheroidal membrane, which had its greatest degree of clinical exposure in the mid-1990s (1). Problems with the genitourinary spheroidal membrane at that time included the lack of ability for secondary and tertiary adjustments as well as the tendency of the device to float into non-therapeutic positions in the retropubic space.…”
mentioning
confidence: 99%