Peritoneal lymphomatosis in a dog after resection of LGL intestinal lymphoma: imaging features

Abstract

A six-year-old intact male Chihuahua dog was referred for vomiting, diarrhoea and weight loss. Ultrasonographic (US) and computed tomographic examination revealed a focal thickening in the jejunum, with no signs of gross metastatic disease. Histology and immunohistochemistry performed after surgical resection revealed a presumed large granular lymphocytic lymphoma. Treatment with chlorambucil was started, and no signs of recurrence were noticed at serial US follow-up for the following months. Six months after surgery, several lesions were seen in the ventrolateral aspect of the peritoneal cavity both on ultrasonography and CT, and cytology confirmed the suspicion of peritoneal lymphomatosis.

Peritoneal lymphomatosis with pleural and peritoneal effusions in a dog: a case report

“…Tumor cells can detach from the primary tumor and float within the peritoneal fluid, leading to their adherence and invasion of the peritoneal surface [5]. Previous reports have described intraperitoneal lesions following tumor resection in dogs and FNA of primary masses in feline colonic lymphoma [2,6]. Tumor cells can disseminate directly from the primary tumor or through iatrogenic processes, potentially resulting in intraperitoneal seeding.…”