Peritoneal dialysis in infants: the experience of the Italian Registry of Paediatric Chronic Dialysis

Vidal, Enrico; Edefonti, Alberto; Murer, Luisa; Gianoglio, Bruno; Maringhini, Silvio; Pecoraro, Carmine; Sorino, Palma; Leozappa, Giovanna; Lavoratti, Giancarlo; Ratsch, Ilse Maria; Chimenz, Roberto; Verrina, Enrico

doi:10.1093/ndt/gfr322

Cited by 68 publications

(80 citation statements)

References 32 publications

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“…[18][19][20][21] It is conceivable that the greater mean weight and mean weight z score observed in the recent temporal cohort of the infant group likewise reflect the combined benefit of all these improvements and also may have contributed to the improved patient survival.…”

Section: Discussionmentioning

confidence: 99%

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

2015

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Section: Discussionmentioning

confidence: 99%

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

2015

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“…Such is the current expertise that in those units that have the resources, RRT can be offered from birth [7,8]. Increasingly, ethical dilemmas arise in relation to the treatment of those with comorbidities or syndromes [9,10].…”

Section: Introductionmentioning

confidence: 99%

Psychosocial support for children and families requiring renal replacement therapy

Watson

2013

Pediatr Nephrol

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Chronic kidney disease (CKD) and the need for renal replacement therapy (RRT) can place a great strain on the child and family. As well as the medical and nutritional prescription, each child and family requires an individual psychosocial prescription that requires input from multiprofessional team members. The information needs of each child and family need to be constantly evaluated as well as the choice of therapy in relation to social, psychological and economic factors. Many tertiary units lack adequate "time" to deliver such assessments and coordinate the support and respite care for those on long-term dialysis, especially when significant numbers of children are now accepted onto RRT programmes with co-morbidities. National and international standards are needed for the staffing of comprehensive tertiary paediatric renal units as well as studies evaluating supportive care to families.

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“…12,13 Nesta amostra a mortalidade global foi de 30%, embora, tal como descrito na literatura, 6,8,9,15,[19][20][21] se tenha notado uma melhoria desta tendência na última década do estudo e não se tenham registado óbitos de crianças com DRCT primária. A mortalidade em crianças que iniciam DP antes dos dois anos é até quatro vezes superior à encontrada em crianças mais velhas.…”

Section: Discussionunclassified

“…A mortalidade em crianças que iniciam DP antes dos dois anos é até quatro vezes superior à encontrada em crianças mais velhas. 6,8,9,15,[19][20][21] Em séries europeias e norte-americanas publicadas, a taxa de sobrevivência, após um ano em DP, em crianças com idade inferior a dois anos é de cerca de 85%, comparativamente com uma taxa de 95% em crianças que iniciaram DP com idade superior a dois anos. 3,5,6,8,22 No entanto, alguns estudos descrevem que em crianças em DP com idade inferior a dois anos sem comorbilidades associadas, a sobrevida é semelhante à das crianças mais velhas.…”

Section: Discussionunclassified

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Diálise Peritoneal nos Dois Primeiros Anos de Vida: Experiência de uma Unidade de Nefrologia e Transplantação Renal Pediátrica

Deuchande¹,

Mano

Novais³

et al. 2016

Acta Med Port

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Introduction:Peritoneal dialysis is the dialytic method of choice in chronic end-stage renal disease in children. This study main purpose was to characterize the long-term survival of a pediatric population who began peritoneal dialysis within the first two years of life. Material and Methods: A descriptive and retrospective study was performed in a portuguese nephrology and renal transplantation pediatric unit, between January 1991 and August 2014. End-stage renal disease etiology, mortality, comorbidities and complications of peritoneal dialysis and end-stage renal disease, growth and psychomotor development were evaluated. Results: Twenty children started peritoneal dialysis within the first two years of life. There were six deaths, but no deaths of children with primary chronic kidney disease were registered over the past decade. The 14 living children were characterized; 13 were males. Congenital abnormalities of the kidney and urinary tract were the leading etiology of chronic kidney disease (45%). The average age start of peritoneal dialysis was 6.1 months; six children started before 30 days of life. Peritonitis was the most frequent cause of hospitalization. Ten children were transplanted at an average age of 5.3 years. All of the children who are still in peritoneal dialysis have short stature, but nine of the transplanted have final height within the expected for their mid-parental height target range. Nine (64%) had some type of neurodevelopmental delay. Discussion: Peritoneal dialysis is a technique possible and feasible since birth, as evidenced in the study, as more than half of children successfully started it before 6 months of life. It allows long-term survival until the possibility of renal transplantation despite the associated morbidity, including peritonitis and complications of chronic renal disease. The ten transplanted children improved their growth, recovered from chronic anemia and improved dyslipidemia, compared with the period of dialysis. However, the average waiting time until the renal transplant was 5.3 years higher than other international centers. Conclusion: These data support the use of peritoneal dialysis from birth, but complications and the worst growth reflect the need to develop strategies to optimize care relating to nutrition, growth and development and to reduce pre-transplant time.

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Peritoneal dialysis in infants: the experience of the Italian Registry of Paediatric Chronic Dialysis

Cited by 68 publications

References 32 publications

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

Psychosocial support for children and families requiring renal replacement therapy

Diálise Peritoneal nos Dois Primeiros Anos de Vida: Experiência de uma Unidade de Nefrologia e Transplantação Renal Pediátrica

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