Peritoneal changes due to laparoscopic surgery

Brokelman, Walter J.A.; Lensvelt, Mare M.A.; Rinkes, I.H.M. Borel; Klinkenbijl, Jean H. G.; Reijnen, Michel M.P.J.

doi:10.1007/s00464-010-1139-2

Cited by 91 publications

(73 citation statements)

References 73 publications

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“…The protective function of the peritoneum can be disturbed by the physical as well as the chemical action of the gas used to create a pneumoperitoneum. As a result, immunological, inflammatory and angiogenic imbalances occur [1].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of peritoneal tissue by means of differential scanning calorimetry (DSC)

Torres¹,

Trębacz²,

Chróścicki³

et al. 2012

Folia Histochem Cytobiol.

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Abstract:Abdominal surgeries alter the integrity of the peritoneal layer and cause imbalances among immunological, inflammatory and angiogenic mechanisms within the tissue. During laparoscopic procedures a protective function of the peritoneal layer can be disturbed by the gas used to create a pneumoperitoneum. The aim of this study was to characterize peritoneal tissue by means of differential scanning calorimetry (DSC) as a reference for future investigations on the influence of surgical procedures on the physicochemical state of the peritoneum. Thirty-seven patients participated in the study. Patients were divided into three groups according to the type of surgery: group H -patients who underwent hernia repair; group Ch -patients who underwent laparoscopic cholecystectomy; and group C -patients operated due to rectal cancer. It was observed that onset temperature (T o ), denaturation temperature (T m ) and change of enthalpy (DH) during thermal denaturation of peritoneal collagen in were significantly different for these three groups of patients. The mean values of onset temperature (T o ) and denaturation temperature (T m ) in group H were significantly lower, while DH in this group was significantly higher than in the two other groups (Ch and C). This preliminary study does not answer whether the differences in collagen denaturation found in peritoneal tissue from different groups of patients resulted from a different inherent state of the tissue, or from surgical procedures. However, the results suggest that DSC is an appropriate method to study subtle changes in the physicochemical condition of the peritoneum using small samples obtained during surgical procedures.

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Section: Introductionmentioning

confidence: 99%

Evaluation of peritoneal tissue by means of differential scanning calorimetry (DSC)

Torres¹,

Trębacz²,

Chróścicki³

et al. 2012

Folia Histochem Cytobiol.

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“…One was the decreased viability of mesothelial cells as effect of CO 2 insufflation during the laparoscopic cholecystectomy procedures. Elevated intra-abdominal pressure restrains blood perfusion and initiates intraperitoneal acidosis [21,22]. However, an excess of carbon dioxide is potentially harmful to human cells.…”

Section: Discussionmentioning

confidence: 99%

The Impact of 0.9% NaCl on Mesothelial Cells After Intraperitoneal Lavage During Surgical Procedures

2016

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“…The benefits of laparoscopic or minimally invasive surgery (better cosmesis, reduced postoperative pain, and faster recovery) are well known for many diseases, but reduced trauma to the abdominal wall is particularly evident in pancreatic surgery. [1,2] However, surgery of the pancreas is still challenging, and although the first reported case of laparoscopic approach in pancreatic disease was in 1994, it has been widely applied only in the past decade. [3][4][5] Open surgery is still performed because of the anatomy of pancreas, limitations of team skills, and some early concerns regarding oncologic outcomes.…”

Section: Introductionmentioning

confidence: 99%

Mini-invasive distal pancreatectomy: a feasible and cost-effective technique

Basso¹,

Maffeis²,

Lumachi³

et al. 2017

MIS

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Aim: Laparoscopic pancreatic surgery is a minimally invasive technique that has been widely applied only in the past decade. The purpose of this study was to evaluate its safety and assess whether laparoscopic distal pancreatectomy (LDP) is cost-effective compared with open distal pancreatectomy (ODP). Methods: The medical records of patients treated for leftsided pancreatic lesions were retrospectively analysed, and the analysis of costs for hospital stay, operative time, and equipment were analysed. Twelve patients underwent LDP, while 12 patients underwent ODP. Results: The two groups were homogeneous according to age, ASA score, BMI, and distribution of pathological findings. Both the size of the specimen (5.33 ± 3.2 vs. 5.58 ± 2.57 cm) and the number of removed lymph nodes (10.5 ± 4.3 vs. 12.1 ± 3.1) did not differ. Although LDP required a longer operative time (197.5 ± 33.7 vs. 122.5 ± 35.4 min), intraoperative bleeding, postoperative pain intensity (measured by VAS scale) and hospital stay were significantly reduced. Conclusion: The mini-invasive approach offers several advantages compared with open surgery, including a significant reduction of blood loss and postoperative pain, and an earlier recovery. The global costs of laparoscopic surgery should be carefully re-evaluated, considering the saving that arises from these advantages. Key words:Mini-invasive, distal pancreatectomy, laparoscopy, cost ABSTRACTArticle history:

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Peritoneal changes due to laparoscopic surgery

Cited by 91 publications

References 73 publications

Evaluation of peritoneal tissue by means of differential scanning calorimetry (DSC)

Evaluation of peritoneal tissue by means of differential scanning calorimetry (DSC)

The Impact of 0.9% NaCl on Mesothelial Cells After Intraperitoneal Lavage During Surgical Procedures

Mini-invasive distal pancreatectomy: a feasible and cost-effective technique

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