2007
DOI: 10.1007/s00464-007-9409-3
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Peritoneal and systemic pH during pneumoperitoneum with CO2 and helium in a pig model

Abstract: Insufflation of CO(2) into the peritoneal cavity seemed to result in an immediate decrease in peritoneal pH, a response that might influence biological events. This peritoneal effect also seems to influence systemic acid-base balance, probably due to trans-peritoneal absorption.

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Cited by 38 publications
(26 citation statements)
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References 14 publications
(13 reference statements)
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“…With the exception of the lower peritoneal IL-6 response, the local cytokine response was otherwise similar after laparoscopy compared with laparotomy, with no difference in the three other cytokines measured. This may be because of the known local immunologic effects of desiccation and acidification caused by the formation of carbonic acid during carbon dioxide pneumoperitoneum [20,[59][60][61][62][63][64][65][66][67][68].…”
Section: Discussionmentioning
confidence: 97%
“…With the exception of the lower peritoneal IL-6 response, the local cytokine response was otherwise similar after laparoscopy compared with laparotomy, with no difference in the three other cytokines measured. This may be because of the known local immunologic effects of desiccation and acidification caused by the formation of carbonic acid during carbon dioxide pneumoperitoneum [20,[59][60][61][62][63][64][65][66][67][68].…”
Section: Discussionmentioning
confidence: 97%
“…Few reports of adhesions after laparoscopy exist [7][8][9]. Experimental studies have demonstrated that several factors, such as CO 2 -induced acidosis and metabolic hypoxemia, temperature, and duration of the intervention, are important in the formation of adhesions at laparoscopy [10]. In an experimental model in pigs, it was reported recently that the incidence of intra-abdominal adhesions was lower after laparoscopic compared with open cholecystectomy [11].…”
mentioning
confidence: 99%
“…A elevação da pressão intraperitoneal e potencial absorção de CO 2 , condição que pode levar a aumento significativo da pressão parcial de CO 2 e diminuição da pressão parcial arterial de O 2 (Vannozzi et al 2002), podem causar alterações no equilíbrio acidobásico, ventilatórias e hemodinâ-micas, além de hipercapnia e acidose (Botter et al 2005, Bergstrom et al 2007, porém em todos os procedimentos não houve alterações mensuráveis compatíveis com as citadas.…”
Section: Resultsunclassified