Peristeen integrated transanal irrigation system successfully treats faecal incontinence in children

Corbett, Philip; Denny, A.; Dick, Karen; Malone, P.S.; Griffin, Stephen; Stanton, Michael

doi:10.1016/j.jpurol.2013.08.006

Cited by 59 publications

(44 citation statements)

References 16 publications

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“…Five studies evaluated relationships between methods of bowel management and HRQOL in children with MMC. Three longitudinal studies (Ausili et al ; Corbett et al ; Midrio et al ) have demonstrated that there are measurable improvements in faecal incontinence and QOL when using transanal irrigation system. Ok and Kurzrock () observed a significant improvement in faecal incontinence and QOL scores among patient with SB who underwent the Malone antegrade continence enema procedure.…”

Section: Resultsmentioning

confidence: 99%

Health‐related quality of life in children with myelomeningocele: a systematic review of the literature

Bakanienė

Prasauskienė

Vaičienė-Magistris

2016

Child

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Myelomeningocele (MMC) is the most complex congenital birth defect compatible with life. To provide the best health care for children with MMC, clinicians and researchers have to understand health and functional status of their patients as well as factors influencing their quality of life (QOL). The objective is to review studies that assess health-related quality of life (HRQOL) and determinants of HRQOL in children with MMC. The data sources include MEDLINE, along with reference lists of relevant reviews and included articles. Study eligibility criteria are quantitative studies that assess HRQOL using validated HRQOL instrument. Participants include children aged 0-18 years with diagnosis of MMC or spina bifida. Risk of bias was assessed using the Hayden system for non-randomized studies. Narrative synthesis and tables of results of HRQOL studies were conducted. Children with MMC have decreased HRQOL compared with normative population. Physical HRQOL is the most exposed aspect of QOL, while discrepancies in psychosocial domains vary by study. Many determinants of QOL have been found, and it is still not clear which determinant can be described as the strongest predictor. Psychosocial factors are the most consistent determinants of HRQOL.Heterogeneous study sample size, study designs, determinant and outcomes measures limited synthesis of findings. The HRQOL in children with MMC is complex and mediated by a number of associated medical problems, together with a variety of psychosocial and environmental factors. Future research is needed (a) on the relation between complex medical problems, functional independence, parent's and clinician's expectation and HRQOL in children and (b) to assess the differences in HRQOL by social environment and healthcare system.

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Section: Resultsmentioning

confidence: 99%

Health‐related quality of life in children with myelomeningocele: a systematic review of the literature

Bakanienė

Prasauskienė

Vaičienė-Magistris

2016

Child

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“…However, this analysis did not examine whether patients undergoing ACE or colostomy procedures were more or less likely to identify themselves as “continent” compared to patients receiving medical management alone or no management. Given recent advances with cone enemas or the Peristeen ® anal irrigation system, this is clearly an area that merits further study [16]. In terms of establishment of applicable standards of care, future analysis will need to focus on the outcomes of all interventions, specifically whether specific interventions or specific clinics with higher surgical rates have higher continence rates.…”

Section: Discussionmentioning

confidence: 99%

Variation in surgical management of neurogenic bowel among centers participating in National Spina Bifida Patient Registry

Routh

Joseph

Liu

et al. 2017

PRM

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PURPOSE Optimal management of neurogenic bowel in patients with spina bifida (SB) remains controversial. Surgical interventions may be utilized to treat constipation and provide fecal continence, but their use may vary among SB treatment centers. METHODS We queried the National Spina Bifida Patient Registry (NSBPR) to identify patients who underwent surgical interventions for neurogenic bowel. We abstracted demographic characteristics, SB type, functional level, concurrent bladder surgery, mobility, and NSBPR clinics to determine whether any of these factors were associated with interventions for management of neurogenic bowel. Multivariable logistic regression with adjustment for selection bias was performed. RESULTS We identified 5,528 patients with SB enrolled in the 2009–14 NSBPR. Of these, 1,088 (19.7%) underwent procedures for neurogenic bowel, including 957 (17.3%) ACE/cecostomy tube and 155 (2.8%) ileostomy/colostomy patients. Procedures were more likely in patients who were older, white, non-ambulatory, with higher-level lesion, with myelomeningocele lesion, with private health insurance (all p < 0.001), and female (p = 0.006). On multivariable analysis, NSBPR clinic, older age (both p < 0.001), race (p = 0.002), mobility status (p = 0.011), higher lesion level (p < 0.001), private insurance (p = 0.002) and female sex (p = 0.015) were associated with increased odds of surgery. CONCLUSIONS There is significant variation in rates of procedures to manage neurogenic bowel among NSBPR clinics. In addition to SB-related factors such as mobility status and lesion type/level, non-SB-related factors such as patient age, sex, race and treating center are also associated with the likelihood of undergoing neurogenic bowel intervention.

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“…Children and their parents should be prepared for a long-term process with many ups and downs. The aim is to prevent accidents and achieve regular bowel emptying, emphasizing the importance of immediately going to the toilet (35,36). In addition, the education of both children and their parents in colorectal physiology, defecation and faecal incontinence can help significantly.…”

Section: Treatmentmentioning

confidence: 99%

Encopresis in Children: An Overview of Recent Findings

Vuletic

2017

Serbian Journal of Experimental and Clinical Research

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Peristeen integrated transanal irrigation system successfully treats faecal incontinence in children

Cited by 59 publications

References 16 publications

Health‐related quality of life in children with myelomeningocele: a systematic review of the literature

Health‐related quality of life in children with myelomeningocele: a systematic review of the literature

Variation in surgical management of neurogenic bowel among centers participating in National Spina Bifida Patient Registry

Encopresis in Children: An Overview of Recent Findings

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