Perirenal soft tissue infiltration from immunoglobulin G4–related disease

Chen, Po-Ting; Chang, Koping; Liu, Kao–Lang

doi:10.1503/cmaj.180264

Cited by 2 publications

(2 citation statements)

References 3 publications

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“…Perirenal soft tissue infiltration associated with IgG4-RD is rare ( 2 ). Cho et al and Chen et al reported perirenal capsule infiltration due to IgG4-RD ( 3 , 4 ). Kidney failure was mild and not rapidly progressive in these cases, and the detailed mechanism underlying the development of kidney failure was not explained.…”

Section: Discussionmentioning

confidence: 99%

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Rapidly Progressive Kidney Failure Associated with Perirenal Capsular Lesion Due to IgG4-Related Disease

et al. 2021

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A 71-year-old Japanese man with progressive kidney failure was referred to our hospital. Laboratory tests showed elevated IgG4 levels. Contrast-enhanced computed tomography (CT) revealed soft tissue surrounding the left kidney and right atrophic kidney. A histopathological examination revealed inflammation and fibrosis with rich IgG4-positive cells in the thickened kidney capsule, but not in the kidney parenchyma. Poor enhancement in the left kidney on contrast-enhanced CT and wrinkling of glomerular capillaries in pathological tissues were also observed. These findings indicated IgG4-related perirenal lesions leading to low renal perfusion and kidney failure. The perirenal lesions and kidney failure were improved by corticosteroid therapy.

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Section: Discussionmentioning

confidence: 99%

“…Hydronephrosis associated with retroperitoneal fibrosis is another common abnormality. Perirenal lesions are a rare presentation of IgG4-RD and few studies have reported on their clinical significance in detail ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%