Periprosthetic Joint Infection after Shoulder Arthroplasty

Sendi, Parham; Moor, Beat K.; Zumstein, Matthias A.

doi:10.1002/9781118581742.ch10

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Factors Potentially Influencing Synovial Wbc Count Thresholds1

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2019

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“…Sixteen of these cases (84%) were diagnosed with infection; the optimal synovial WBC count threshold was 12,200 cells/μL (sensitivity 92% and specificity 100%) and the optimal PMN% threshold was 54 (sensitivity 100% and specificity 75%). This higher threshold for infection in shoulders compared with hips and knees was also observed in previous reports 59. These data indicate that a different threshold should be applied for shoulder arthroplasties, but larger studies are needed to confirm these findings.…”

Section: Factors Potentially Influencing Synovial Wbc Count Thresholdssupporting

confidence: 83%

Factors to Consider When Assessing the Diagnostic Accuracy of Synovial Leukocyte Count in Periprosthetic Joint Infection

Ottink

Strahm

Muller-Kobold

et al. 2019

J. Bone Joint Infect.

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Abstract. Synovial white blood cell (WBC) count and the percentage of polymorphonuclear leucocytes (PMN%) is one of the diagnostic criteria to diagnose a periprosthetic joint infection (PJI). Although the test is widely available, the diagnostic accuracy of proposed cut-off levels are influenced by several factors, such as: the affected joint, co-morbid conditions, the causative microorganism and the gathering and processing of samples in the laboratory. In this narrative review we provide an overview on how and to what extent these factors can affect the synovial WBC count and PMN% in synovial fluid.

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Section: Factors Potentially Influencing Synovial Wbc Count Thresholdssupporting

confidence: 83%