Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults

Byrne, Anthony; Bennett, Michael H; Pace, Nathan L.; Thomas, Paul S.

doi:10.1002/14651858.cd010841

Cited by 16 publications

(10 citation statements)

References 44 publications

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“…The PVBG might be useful in determining that the venous blood has a very low amount of CO 2 and a very high O 2 to exclude hypercapnia and hypoxia, respectively, and this is the subject of a separate formal Cochrane diagnostic test accuracy review …”

Section: Discussionmentioning

confidence: 99%

“…This has important implications for the use of PVBG as a replacement test for ABG analysis, especially among diverse and unwell patient populations such as those in the ED. The question of whether PVBG analyses is a clinically useful test for the diagnosis of respiratory failure is the subject of a separate Cochrane review under way at present …”

Section: Discussionmentioning

confidence: 99%

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Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

et al. 2014

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Peripheral venous blood gas (PVBG) analysis is increasingly being used as a substitute for arterial blood sampling; however, comparability has not been clearly established. To determine if the pH, PCO2 and PO2 obtained from PVBG analysis is comparable with arterial blood gas (ABG) analysis. A search was conducted of electronic databases as well as handsearching of journals and reference lists through December 2012 to identify studies comparing PVBG with ABG analysis in adult subjects. A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. A meta-analysis using a random effects model was used to calculate the average difference (bias) and the limits of agreement for the venous and arterial pH, PCO2 and PO2. A total of 18 studies comprising 1768 subjects were included in the meta-analysis. There was considerable heterogeneity between studies with I 2 approaching 100%. There was little difference between the pH obtained from the PVBG and the ABG, with the arterial pH typically 0.03 higher than the venous pH (95% confidence interval 0.029-0.038). The venous and arterial PCO2 were not comparable because the 95% prediction interval of the bias for venous PCO2 was unacceptably wide, extending from −10.7 mm Hg to +2.4 mm Hg. The PO2 values compared poorly, the arterial PO2 typically 36.9 mm Hg greater than the venous with significant variability (95% confidence interval from 27.2 to 46.6 mm Hg). PVBG analysis compares well with ABG analysis for pH estimations in adults but not to the PCO2 or PO2. These differences are sufficiently large to be of clinical significance.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

et al. 2014

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“…Our meta‐analysis and Cochrane analysis suggest that the existing data do not support using VBG for respiratory failure as the agreement is poor and could lead to inappropriate management decisions . Wong et al .…”

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confidence: 74%

Arterial and venous blood gases in exacerbations of chronic obstructive pulmonary disease

Byrne

Bennett

Chatterji

et al. 2020

Internal Medicine Journal

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“…Blood gas analysis performed using a venous blood sample is sufficient to assess tissue pH and electrolyte and lactate levels but cannot accurately detect partial carbon dioxide pressure (PaCO 2 ). [ 5 6 7 8 9 10 11 12 ] PaCO 2 in venous blood measures tissue carbon dioxide and does not reflect the arterial PaCO 2 value. Since the bicarbonate level is calculated by an indirect method using pH and pCO 2 and the Henderson–Hasselbach equation in blood gas analyses, the blood gas analysis of venous samples does not show the bicarbonate level accurately.…”

Section: 2 Arterial Blood Gas Evaluationmentioning

confidence: 99%

2021 Guideline for the Management of COPD Exacerbations: Emergency Medicine Association of Turkey (EMAT) / Turkish Thoracic Society (TTS) Clinical Practice Guideline Task Force

Doğan¹,

Varol²,

Köktürk³

et al. 2021

Turk J Emerg Med

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Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults

Abstract: Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults.

Cited by 16 publications

References 44 publications

Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta‐analysis

Arterial and venous blood gases in exacerbations of chronic obstructive pulmonary disease

2021 Guideline for the Management of COPD Exacerbations: Emergency Medicine Association of Turkey (EMAT) / Turkish Thoracic Society (TTS) Clinical Practice Guideline Task Force

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