“…Corcos et al 188 have determined through biopsy of the dorsal pedal vein that the degree of intimal thickening, ectasia, muscular hyperplasia, medial fibrosis, fragmentation, and dissociation of the internal elastic membrane and intimal fibrous plaques correlate with the concentration of sclerosing solution necessary to effect endosclerosis of varicose veins. Corcos et al 188 have determined through biopsy of the dorsal pedal vein that the degree of intimal thickening, ectasia, muscular hyperplasia, medial fibrosis, fragmentation, and dissociation of the internal elastic membrane and intimal fibrous plaques correlate with the concentration of sclerosing solution necessary to effect endosclerosis of varicose veins.…”