Peripheral ulcerative keratitis `corneal melt' and rheumatoid arthritis: a case series

Abstract

RA-associated PUK often has a poor visual outcome and its appearance may herald the transformation of a patient's RA into the systemic vasculitic phase. RA-associated PUK should be managed with aggressive immunosuppression if the associated morbidity and mortality are to be avoided. Cell-mediated mechanisms appear to be important in the aetiopathogenesis of PUK and a combination of corticosteroids and cyclosporin is therefore probably the regimen of choice.

Clinical review of corneal ulcers resulting in evisceration and enucleation in elderly population

“…Thirty patients (64%) underwent evisceration, and 17 (36%) underwent enucleation. The number of females (24) was higher than the number of males (23). Mean age of these patients at the time of diagnosis was 81±9.39 years (range: 62-100 years).…”

A Case of Peripheral Ulcerative Keratitis in a Patient with Rheumatoid Arthritis

“…In a severe case of PUK, corneal deterioration may lead to irreversible loss of vision (1). We here present a case of PUK in a patient with long standing RA.…”

Sudden Onset Blindness in a Patient with Mixed Connective Tissue Disease

“…10,11 The two principal ocular manifestations of rheumatoid vasculitis are episcleritis and peripheral ulcerative keratitis. 12,13 The presence of an elevated RF and positive ANA, as well as a past medical history of nodular episcleritis, led to a high clinical suspicion for rheumatoid vasculitis.…”