Peripheral T-cell lymphoma in a patient with the acquired immunodeficiency syndrome

AIDS-related Primary Pulmonary Lymphoma

“…The standardized incidence rate was estimated at 0 to 0.3 per 100 person-yr in our cohort of 4,700 HIV-infected adults, and, using the same diagnostic criteria as in this study, we found only 16 such cases in the literature between 1980 and 1996 (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(22)(23)(24)(25)(26)(27)(28). One of the latter cases was included in the present series (Patient 10) (11).…”

“…Five cases of AIDS-related PPL published in the literature were of the T-cell lineage (12,15,18,19,21). This is unexpected, as T-cell lymphoma accounts for only a few percent of all cases of AIDS-related NHL (1,2).…”

“…This is unexpected, as T-cell lymphoma accounts for only a few percent of all cases of AIDS-related NHL (1,2). Four cases in the literature were described as diffuse, mixed (small and large) cell NHL, according to the Working Formulation (18)(19)(20)(21) or as intermediate or high-grade malignant lymphomas in the updated Kiel classification. By contrast, almost all our cases of AIDS-related PPL were high-grade B-cell NHL.…”

“…This is usually associated with other sites of disease and is found during the staging process. The lung is rarely the initial or only site of involvement, and only a few case reports of AIDS-related primary pulmonary lymphoma (PPL) have been published (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). The aim of this study was to describe the clinical characteristics, pathologic findings, and role of EBV infection in 12 cases of histologically proven AIDSrelated PPL.…”