Peripheral pulmonic stenosis

Delaney, Thomas B.; Nadas, Alexander S.

doi:10.1016/0002-9149(64)90152-3

Cited by 28 publications

(5 citation statements)

References 23 publications

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“…The murmur usually disappears by 3-6 months of age. If a murmur persists beyond this age with the same Doppler characteris tics, a structural narrowing of the pulmonary artery tree (peripheral pulmonary artery ste nosis) should be suspected [9][10][11].…”

Section: Functional Murmur and Echocardiographymentioning

confidence: 99%

Doppler Assessment of Physiological Stenosis at the Bifurcation of the Main Pulmonary Artery: A Cause of Functional Murmur in Neonates

So¹,

Watanabe²,

Shimizu³

et al. 1996

Neonatology

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A systolic heart murmur is not infrequently recognized in healthy newborn infants, especially those with a low birth weight. This study aimed at assessing the hemodynamics at the bifurcation of the main pulmonary artery using Doppler echocardiography and to correlate the results with this murmur. The peak velocities of main pulmonary artery (MPAV) and right pulmonary artery (RPAV) were studied in 25 low-birth-weight infants who had recovered from acute stage and presented with a systolic murmur, and the ratio of RPAV/MPAV was calculated. Another compatible 25 healthy low-birth-weight infants without a murmur were enrolled as the control group. The initial MPAV values were 79.8 ± 20.7 (range 51–152) cm/s and 80.7 ± 14.2 (range 60–111) cm/s in the heart murmur group and in the control group, respectively (p > 0.05). The initial RPAV values were 193.4 ± 60.2 (range 118–388) cm/s and 99.8 ± 15.5 (range 76–132) cm/s in the heart murmur group and in the control group, respectively (p < 0.0001). The initial RPAV/MPAV ratios were 2.46 ± 0.61 (1.59–3.92) and 1.25 ± 0.14 (0.94–1.47) in the heart murmur group and in the control group, respectively (p < 0.0001). When the murmur disappeared after a period of 2–5 months, no significant differences in the last RPAV and RPAV/MPAV ratios between both groups could be found. The RPAV in the heart murmur group faded significantly to 118.7 ± 16.9 cm/s, and so did the RPAV/MPAV ratio to 1.24 ± 0.12 (p < 0.0001). A transient functional murmur recognized in healthy premature infants at about 1 month of age is caused by the pressure gradient that implies a physiological stenosis at the bifurcation of the main pulmonary artery. The RPAV is higher than the MPAV, and the RPAV/MPAV ratio is usually over 1.5. The RPAV became slower, and the RPAV/MPAV ratio fell as the murmur faded with age.

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Section: Functional Murmur and Echocardiographymentioning

confidence: 99%

Doppler Assessment of Physiological Stenosis at the Bifurcation of the Main Pulmonary Artery: A Cause of Functional Murmur in Neonates

So¹,

Watanabe²,

Shimizu³

et al. 1996

Neonatology

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“…The high frequency murmur of pulmonary incompetence has not been specifically described, though in one case there was an early diastolic blowing murmur in the second left interspace (Delaney and Nadas, 1964). Graham Steell murmurs are unlikely, despite considerable pulmonary hypertension.…”

Section: Discussionmentioning

confidence: 96%

“…If the intensity of pulmonary closure were influenced by the abruptness with which the leaflets seat, then the resulting sound should be increased. Though some observers have described a relatively loud pulmonary component of the second heart sound (Delaney and Nadas, 1964;Gyllensward et al, 1957), others have not found a uniform increase in intensity (Perloff, 1967;Venables, 1965;Franch and Gay, 1963;D'Cruz et al, 1964;Arvidsson et al, 1961;Bourassa and Campeau, 1963;Dighiero et al, 1957). In any event, in valvular or subvalvular pulmonary stenosis, the loudness of pulmonary closure usually varies inversely with the degree of obstruction (Perloff, 1963), whereas in pulmonary artery stenosis, the intensity is maintained but not necessarily increased as the obstruction becomes more severe.…”

Section: Discussionmentioning

confidence: 99%

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Auscultatory and phonocardiographic manifestations of isolated stenosis of the pulmonary artery and its branches.

Perloff¹,

LeBauer²

1969

Heart

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“…The prevalence of isolated pulmonary artery branch steno-sis is uncertain. Delaney et al (9) found only 4 cases among 3,250 right heart catheterization and described isolated pulmonary artery branch stenosis as a relatively rare disease. In general, patients are asymptomatic unless they have suprasystemic right ventricular pressure or associated cardiac disease, thus the prevalence of isolated pulmonary artery branch stenosis may be underestimated.…”

Section: F I G U R E 3 P E R F U S I O N S C a N N I N G S H O We Dmentioning

confidence: 99%

A Case of Isolated Peripheral Pulmonary Artery Branch Stenosis Associated with Multiple Pulmonary Artery Aneurysms

et al. 2010

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Selective right pulmonary arteriography and 3-dimensional computed tomography revealed multiple severe stenoses of the peripheral pulmonary artery associated with poststenotic aneurysms in a 65-year-old woman. She was referred to the hospital for evaluation of dry cough, gradually increasing dyspnea and multiple nodular shadows on a chest radiograph. Echocardiography and cardiac catheterization showed severe pulmonary hypertension, though other structural heart diseases or well-characterized congenital syndromes were ruled out. She was diagnosed as isolated peripheral pulmonary artery branch stenosis. Recent advances in CT technology enable a less-invasive assessment of pulmonary artery, and can be useful in the management of pulmonary arterial hypertension.

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Peripheral pulmonic stenosis

Cited by 28 publications

References 23 publications

Doppler Assessment of Physiological Stenosis at the Bifurcation of the Main Pulmonary Artery: A Cause of Functional Murmur in Neonates

Doppler Assessment of Physiological Stenosis at the Bifurcation of the Main Pulmonary Artery: A Cause of Functional Murmur in Neonates

Auscultatory and phonocardiographic manifestations of isolated stenosis of the pulmonary artery and its branches.

A Case of Isolated Peripheral Pulmonary Artery Branch Stenosis Associated with Multiple Pulmonary Artery Aneurysms

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