Peripheral MR Angiography

Kramer, J. Harald; Grist, Thomas M.

doi:10.1016/j.mric.2012.08.002

Cited by 13 publications

(8 citation statements)

References 49 publications

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“…For patients with peripheral arterial occlusive disease (PAOD) contrast-enhanced MRA has become the most appropriate noninvasive diagnostic method of choice [16]. Systematic reviews have confirmed the high diagnostic accuracy of peripheral CE-MRA [5].…”

Section: Discussionmentioning

confidence: 99%

Steady state vascular imaging with extracellular gadobutrol: evaluation of the additional diagnostic benefit in patients who have undergone a peripheral magnetic resonance angiography protocol

Ong

Hausotter

Pilz

et al. 2013

Journal of Cardiovascular Magnetic Resonance

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BackgroundTo evaluate the feasibility and additional diagnostic benefit of a high-resolution steady state 3D-volume interpolated breath-hold exam (VIBE) sequence between a continuous table movement (CTM) MR angiography of the entire runoff vasculature and a time-resolved (TWIST) MRA of the calves.MethodsIn this retrospective IRB approved study 224 patients (72 women, 152 men, mean age 67.29 ± 13.9) were included who had undergone a low-dose MR angiographic protocol at 3T (Siemens TimTrio) after injection of 0.1 mmol/kg gadobutrol including a CTM MRA, a time-resolved MRA of the calf station and a steady state 3D VIBE sequence prior to the time-resolved MRA. One board-certified radiologist rated the image quality of the steady state VIBE sequences on an ordinal three point scale (excellent, good, poor) and analyzed the images for additional diagnostic findings of and beyond the vascular system in comparison to the CTM MRA and the time-resolved MRA. Descriptive statistics and demographic patient data were used for further evaluation.ResultsThe image quality of the steady state imaging of the pelvis, upper and lower leg was excellent in up to 88%, 84% and 47%, respectively, while poor image quality was only detected in the upper (2%) and lower leg (6%). An additional diagnostic benefit was found in 44% of the patients overall. The most common relevant pathologies included inflammatory processes of the soft tissues (26%), thrombi (14%), abscesses (13%) and tumors (11%). In subgroups of patients above the age of 60, 65, 70, 75 and 80 years an additional pathology was found in 50% 33%, 44%, 65% and 58%, respectively. There was no significant difference in terms of additional findings between men and women (46% and 39%, p > 0.05) and inpatients and outpatients (42% and 45%, p > 0.05).ConclusionSteady state imaging is also feasible with extracellular contrast agents with good image quality yielding additional diagnostic findings in up to 44% and above in patients older than 60 years of age irrespective of gender or patient status. Given the short acquisition time of 4 minutes this sequence could be added to all peripheral MRA exams.

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Section: Discussionmentioning

confidence: 99%

Steady state vascular imaging with extracellular gadobutrol: evaluation of the additional diagnostic benefit in patients who have undergone a peripheral magnetic resonance angiography protocol

Ong

Hausotter

Pilz

et al. 2013

Journal of Cardiovascular Magnetic Resonance

View full text Add to dashboard Cite

show abstract

“…3 A high-field magnetic resonance (MR) scanner (1.5T or 3T) with modern phasedarray receive coils is necessary to obtain images with high spatial resolution and high signal-tonoise ratio, while still covering the region of interest. Dedicated phased-array extremity or wrist coils should be used whenever possible, depending on the region of interest and required coverage.…”

Section: Mra Techniquesmentioning

confidence: 99%

“…3 CE-MRA relies on the T1 shortening effect of paramagnetic GBCAs. This results in a significant difference in signal intensity between blood and adjacent tissue when using heavily T1-weighted arterial-phase imaging.…”

Section: Contrast-enhanced Mra Techniquesmentioning

confidence: 99%

“…This results in a significant difference in signal intensity between blood and adjacent tissue when using heavily T1-weighted arterial-phase imaging. 3 The image acquisition must be timed with the contrast bolus peak during the sampling of the center of k-space to achieve maximum vessel contrast. Before the contrast material is injected, a nonenhanced acquisition with the same sequence settings as the contrast-enhanced scans can be acquired to allow for subtraction with the subsequent arterial-phase images.…”

Section: Contrast-enhanced Mra Techniquesmentioning

confidence: 99%

“…These artifacts can impede assessment of vascular disease, potentially causing falsepositive overdetection of vascular stenoses. 3 Phase-contrast MRA PC MRA requires the acquisition of 2 or more (typically 4) data sets 13 or flow-compensated pulses to generate flow-sensitive phase images. Phase data can be used either to reconstruct velocity-encoded flow-quantification images or MRA images.…”

Section: Noncontrast Mramentioning

confidence: 99%

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