Peripheral input and phantom limb pain: A somatosensory event‐related potential study

Liu, Hongcai; Andoh, Jamila; Lyu, Yuanyuan; Milde, Christopher; Desch, Simon; Zidda, Francesca; Schmelz, Martin; Curio, Gabriel; Flor, Herta

doi:10.1002/ejp.1579

Cited by 6 publications

(3 citation statements)

References 61 publications

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“…Transcutaneous electrical nerve stimulation (TENS) is another technique tested for its ability to reduce PLP and reverse the loss of afferent input to the cortex. TENS, 89 direct stimulation of the nerve stumps of the limb manifesting PLP, 90 reduces the pain levels, although long-term pain relief has not been achieved.…”

Section: Reducing Plpmentioning

confidence: 99%

Evolving techniques for reducing phantom limb pain

Kuffler

2023

Exp Biol Med (Maywood)

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At least two million people in the United States of America live with lost limbs, and the number is expected to double by 2050, although the incidence of amputations is significantly greater in other parts of the world. Within days to weeks of the amputation, up to 90% of these individuals develop neuropathic pain, presenting as phantom limb pain (PLP). The pain level increases significantly within one year and remains chronic and severe for about 10%. Amputation-induced changes are considered to underlie the causation of PLP. Techniques applied to the central nervous system (CNS) and peripheral nervous system (PNS) are designed to reverse amputation-induced changes, thereby reducing/eliminating PLP. The primary treatment for PLP is the administration of pharmacological agents, some of which are considered but provide no more than short-term pain relief. Alternative techniques are also discussed, which provide only short-term pain relief. Changes induced by various cells and the factors they release are required to change neurons and their environment to reduce/eliminate PLP. It is concluded that novel techniques that utilize autologous platelet-rich plasma (PRP) may provide long-term PLP reduction/elimination.

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Section: Reducing Plpmentioning

confidence: 99%

Evolving techniques for reducing phantom limb pain

Kuffler

2023

Exp Biol Med (Maywood)

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“…Although SEP responses depend on the stimulus type and characteristics, the SEP components are generally described based on their polarities (positive (P), negative (N)), amplitudes, and latencies. This method has been used in studies with PLP patients to investigate somatosensory and cortical functionality (Herta Flor, 2002aLiu et al, 2020). Alteration in somatosensory cortex activity has been reported in PLP patients by assessing the short (<50 ms after stimulus) (Granata et al, 2018) and long term (>50 ms after stimulus) (D'Anna et al, 2017;Zhao et al, 2016) SEP components.…”

Section: Somatosensory Evoked Potentials (Sep)mentioning

confidence: 99%

Towards Understanding the Neurobiological Effects of Modulated Tens

Jadidi¹

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“…O segundo tipo utiliza medidas objetivas de fenômenos que estão associados à dor, como a taquicardia, lacrimejamento, hipertensão arterial, concentração plasmática de catecolaminas, grau de vasoconstricção da pele, potencial evocado, entre outras. 77,78 Neste trabalho, as medidas para a intensidade da dor foram feitas por três escalas distintas, com o objetivo de se obter maior precisão, já que na casuística participaram pacientes com os mais variados graus de instrução. Na maior parte dos ensaios clínicos, a dor é quantificada por meio de escalas.…”

Section: Fonte: Próprio Autorunclassified

Mapeamento da dor pós-operatória no Hospital das Clínicas de Ribeirão Preto

Daroz

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À minha família por serem capazes de entender as inúmeras horas de minha ausência, necessárias para a elaboração e execução deste trabalho.Ao Prof. Dr. Luís Vicente Garcia por sua incondicional ajuda, apoio e paciência.A todos os meus professores na Pós-Graduação, pelo exemplo, pela sabedoria e pela disponibilidade.À equipe de funcionários do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto: "ao pessoal de enfermagem", e demais colegas. A todos que formaram nosso grupo de trabalho, na área de recuperação pós-anestésica (RECU) do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto. E por fim, a todos os pacientes atendidos no Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto. Todos foram o meio e o fim de todos os esforços despendidos para conclusão desta pesquisa médica e sem eles nada seria possível. O presente trabalho foi realizado com apoio da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior -Brasil (CAPES) -Código de Financiamento 001 RESUMO DAROZ, R. R. Mapeamento da dor pós-operatória no Hospital das Clínicas de Ribeirão Preto. 2023. Tese (Mestrado) -

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Peripheral input and phantom limb pain: A somatosensory event‐related potential study

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

Cited by 6 publications

References 61 publications

Evolving techniques for reducing phantom limb pain

Evolving techniques for reducing phantom limb pain

Towards Understanding the Neurobiological Effects of Modulated Tens

Mapeamento da dor pós-operatória no Hospital das Clínicas de Ribeirão Preto

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