Peripheral corneal disorders

Robin, Jeffrey B.; Schanzlin, David J.; Verity, Steven M.; Barron, Bruce; Arffa, Robert C.; Suarez, Enrique; Kaufman, Herbert E.

doi:10.1016/0039-6257(86)90049-4

Cited by 109 publications

(66 citation statements)

References 253 publications

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“…A major difference between PMD and KCN is the location of maximal corneal thinning and steepening. In PMD, corneal thinning is more peripheral than in KCN [150]. A study examining the peripheral effect of CXL, using OCT evaluation of the stromal demarcation line, showed that the depth of the CXL effect 3 mm away from the center of the cornea decreases to 65% of the central depth.…”

Section: Resultsmentioning

confidence: 99%

Corneal Collagen Crosslinking: A Systematic Review

Sorkin

Varssano²

2014

Ophthalmologica

160

122

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Keratoconus (KCN) is an ectatic disorder with progressive corneal thinning and a clinical picture of corneal protrusion, progressive irregular astigmatism, corneal fibrosis and visual deterioration. Other ectatic corneal disorders include: post-LASIK ectasia (PLE) and pellucid marginal degeneration (PMD). Corneal crosslinking (CXL) is a procedure whereby riboflavin sensitization with ultraviolet A radiation induces stromal crosslinks. This alters corneal biomechanics, causing an increase in corneal stiffness. In recent years, CXL has been an established treatment for the arrest of KCN, PLE and PMD progression. CXL has also been shown to be effective in the treatment of corneal infections, chemical burns, bullous keratopathy and other forms of corneal edema. This is a current review of CXL - its biomechanical principles, the evolution of CXL protocols in the past, present and future, indications for treatment, treatment efficacy and safety.

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Section: Resultsmentioning

confidence: 99%

Corneal Collagen Crosslinking: A Systematic Review

Sorkin

Varssano²

2014

Ophthalmologica

160

122

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“…In contrast to central herpes simplex keratitis, peripheral herpetic keratitis tends to result in more prolonged, treatment-resistant stromal disease. In addition, it is more frequently accompanied by iritis and keratic precipitates, and also tends to run a more prolonged and refractory course [1,6,9,11]. For this reason, close longitudinal monitoring is recommended for such patients.…”

Section: Discussionmentioning

confidence: 94%

Sectorial keratitis and uveitis: differential diagnosis

Baltatzis

Romero-Rangel

Maleki

2003

Graefe's Arch Clin Exp Ophthalmol

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“…This is considered one of the important points in differentiation with keratoconus, in which the maximum protrusion is within the area of thinning. [9][10][11] Corneal topography with classical pattern of crab-claw appearance is not diagnostic for PMD, as it can present with inferior keratoconus. So, it is recommended to perform more detailed analysis with slit-lamp microscopy, topography, anterior and posterior elevation maps by Scheimpflug imaging and full pachymetric maps that shows 12 mm of corneal coverage for improving the diagnostic accuracy for PMD.…”

Section: 2mentioning

confidence: 99%

Treatment of Pellucid Marginal Degeneration

Farrag¹,

Hussein²,

Ummar³

2017

International Journal of Keratoconus and Ectatic Corneal Diseases

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Purpose: To summarize the recent trends in the treatment of pellucid marginal degeneration (PMD) based on available published data.Method and literature search: A PubMed search was conducted with combinations not limited to the following search terms: Pellucid marginal degeneration, Corneal ectasia, Corneal collagen cross-linking (CXL), Intracorneal ring segments (ICRS), Contact lens, Keratoplasty in corneal ectasia. A review of the search results was performed and relevant articles to the topic were included. Summary:Ophthalmologists have got a wide array of therapeutic modalities for the management of PMD. However, the key to optimal treatment is careful clinical assessment of patients and their visual requirements and tailoring the treatment to individual patients.

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Peripheral corneal disorders

Cited by 109 publications

References 253 publications

Corneal Collagen Crosslinking: A Systematic Review

Corneal Collagen Crosslinking: A Systematic Review

Sectorial keratitis and uveitis: differential diagnosis

Treatment of Pellucid Marginal Degeneration

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