Peripheral calcifying cystic odontogenic tumour and peripheral dentinogenic ghost cell tumour: an updated systematic review of 117 cases reported in the literature

Abstract

Peripheral CCOTs/DGCTs are rare lesions. Most of the lesions were treated by simple excision with or without curettage of the underlying bone. As the recurrence rate is very low, a conservative approach seems to be enough for the great majority of cases.

A multicentre study of 268 cases of calcifying odontogenic cysts and a literature review

“…() provided an excellent review of 45 cases of PCOC published in the English literature and found that patients were most affected in their 60 s, 70 s and 80 s. Individuals in their 20 s were also significantly affected. This was the same age distribution observed by Brazilian researchers in 2016 (Chrcanovic & Gomez, ). Most individuals complain of painless swelling (Buchner et al., ; Resende, Brito, Souza, Gomez, & Mesquita, ), and the clinical appearance of these lesions was variously described as sessile, nodular, smooth‐surfaced, firm, of soft consistency or as a fibrous mass (Buchner et al., ; de Lima, Kitakawa, Almeida, Brandão, & Anbinder, ; Resende et al., ).…”

“…Herein, the maxilla was most affected. According to Chrcanovic and Gomez (), the great majority of cases described in the literature appear as isolated case reports or small case series. Buchner et al.…”

“…Most individuals complain of painless swelling (Buchner et al., ; Resende, Brito, Souza, Gomez, & Mesquita, ), and the clinical appearance of these lesions was variously described as sessile, nodular, smooth‐surfaced, firm, of soft consistency or as a fibrous mass (Buchner et al., ; de Lima, Kitakawa, Almeida, Brandão, & Anbinder, ; Resende et al., ). The erosion of the underlying alveolar bone was not so commonly seen in peripheral COC (Chrcanovic & Gomez, ). The clinical differential diagnosis of PCOC includes common gingival growths of a non‐neoplastic nature and other peripheral odontogenic tumours (Buchner, Merrell, & Carpenter, 2006b).…”

Calcifying odontogenic cyst, dentinogenic ghost cell tumor, and ghost cell odontogenic carcinoma: A systematic review

“…DGCT is a benign neoplasm of odontogenic epithelium predominantly consisting of ameloblastomatous proliferations. Some tumors have a significant component of basaloid hyperchromatic and isomorphic cells, displayed as sheets . Ghost cells and dentin‐like or osteodentin‐like material can also be found .…”

Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: An updated analysis of 170 cases reported in the literature

“…The epidemiological study of such lesions is of great importance because provides information that can improve the diagnostic accuracy and will allow pathologists and surgeons to make informed decisions and to refine treatment plans to optimize clinical outcomes (Chrcanovic and Gomez, 2016;2017a;b). The aim of the present study was to integrate the available data published in the literature on SOT and SOT-LPOC into an updated, comprehensive, comparative analysis of their clinical and radiologic features, and to report the frequency of recurrence of these lesions.…”