Peripheral Blood and Bone Marrow in Dogs Subsequent to the Routing of Splenic Blood into the Systemic Circulation

Lorber, Mortimer

doi:10.1159/000205676

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1962

1978

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Cited by 7 publications

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“…As for the other hematic cells, the literature reports that the count and the half-life of the red cells do not change significantly after portacaval shunt [3,4] whereas the white cell count appears to be reduced [13][14][15]20], A general depression of hemato poiesis was also described [4] suggesting that the first hypothesis, that is the decrease in the platelet production seems to be the most probable.…”

Section: Discussionmentioning

confidence: 99%

Thrombocytopenia and Coagulation Impairment after Portacaval Shunt in the Rat

Doni¹,

Vassanelli²,

Bonadiman³

et al. 1978

Pathophysiol Haemos Thromb

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A study has been performed to evaluate the effect of the portacaval shunt on some coagulation tests in the rats. Thrombocytopenia develops, accompanied by a decrease in the total protein and fibrinogen concentrations. Moreover, the Quick time is lengthened, whereas the partial thromboplastin time is not modified. The maximal amplitude and elasticity of the clot, recorded by thrombelastography, appear reduced, and k is lengthened. The results are discussed.

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Section: Discussionmentioning

confidence: 99%