Peripheral Arterial Disease in HIV Patients Older than 50 Years of Age

Palacios, Rosario; Alonso, Isabel; Hidalgo, Á.; Aguilar, Isabel; Sánchez, Miguel Ángel Goenaga; Valdivielso, Pedro; González-Santos, Pedro; Santos, Jesús

doi:10.1089/aid.2008.0001

Cited by 40 publications

(29 citation statements)

References 30 publications

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“…This is similar to what has been found by others 9 and also may support the contention that the HIV infection-related changes may play a major and independent role in the atherosclerosis process. 29 In this context, the accelerated atherosclerosis process in HIV-infected patients can occur in the absence of detectable viral levels or severe immunodeficiency and has been attributed to a chronic inflammatory state.…”

Section: Discussionsupporting

confidence: 92%

“…11,26 Our main finding supports earlier reports, that HIV-infected patients have a high prevalence of PAD. 9,27 However, our study examined the postexercise changes in the HIV-infected patients who have normal rABI. Thirty (26.5%) of our patients had a significant postexercise drop either in eABI or ASP or both.…”

Section: Discussionmentioning

confidence: 99%

“…[6][7][8] In HIV-infected patients, there is growing evidence suggesting a high prevalence of PAD and a higher risk of developing severe and accelerated atherosclerosis. 9 Peripheral arterial disease is commonly underdiagnosed and not aggressively managed. 10 About 85% of PAD patients can be missed if only the history and physical examination are the determining factors for further investigation in the general population.…”

Section: Introductionmentioning

confidence: 99%

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The Role of Postexercise Measurements in the Diagnosis of Peripheral Arterial Disease in HIV-Infected Patients

et al. 2010

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Peripheral arterial disease (PAD) is a marker of atherosclerosis, which is not well studied in the population with human immunodeficiency virus (HIV). We prospectively enrolled HIV-infected patients who had normal resting ankle-brachial index (rABI) readings. All participants performed either a treadmill walking test (TT) or pedal plantar flexion test (PFT). Patients were divided into 2 groups according to postexercise changes; PAD and No-PAD group. The 2 groups were compared with regard to established cardiovascular disease risk factors and other HIV infection parameters. Peripheral arterial disease was present in 30 (26.5%) of 113 consecutive HIV-infected patients included in the study. Mean age was 47 ± 10 years. The risk factors studied did not differ significantly among the 2 groups except for male gender, which was significantly associated with PAD (RR: 4.15; CI: 1.6 to 11.1: P < .0008). The prevalence of PAD, diagnosed by significant drop in postexercise ABI and ankle pressure in patients with HIV is high.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Role of Postexercise Measurements in the Diagnosis of Peripheral Arterial Disease in HIV-Infected Patients

et al. 2010

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“…In men participating in the Multicenter AIDS Cohort Study, only paresthesia was associated with older age (47.9% in men older than 50 years compared with 30.6% in younger men; Silverberg et al, 2009). Palacios et al (2008) found that HIVinfected patients had greater prevalence of dyslipidemia, diabetes, and symptomatic peripheral arterial disease as compared with healthy controls.…”

Section: Comorbidities and Age In Persons With Hiv Diseasementioning

confidence: 97%

Symptom Disclosure by Older HIV-Infected Persons

Nokes

2011

Journal of the Association of Nurses in AIDS Care

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The life expectancy for persons living with HIV infection is markedly increasing, largely because of the advances made with antiretroviral therapy. In comparison with other older individuals, those infected with HIV tend to have higher rates of liver-related conditions, diabetes, and dyslipidemia, as well as substance use and psychiatric disorders. Although these multimorbidities contribute to the symptom burden, older persons with HIV tend not to disclose symptoms to their health care providers. Culture, religion, age, and race can profoundly affect the way in which symptoms are perceived, and reasons for nondisclosure include attributing symptoms to the "normal" aging process. The purpose of this article is to highlight the unique situation of older patients with HIV regarding symptom disclosure and the need for an integrated treatment plan that includes an environment that promotes patient-provider communication, better day-to-day self-care, and self-management strategies.

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“…Estudios realizados en España han mostrado una mayor prevalencia de enfermedad arterial periférica diagnosticada por ITB en población VIH respecto a la no infectada 12 . Nos proponemos en este estudio evaluar la utilidad del ITB en una cohorte de pacientes con infección VIH, con vistas a determinar cuántos pacientes son reclasifi cados como de alto riesgo gracias al uso de esta técnica frente a las formas usuales de cálculo de dicho riesgo.…”

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