Peripartum Asphyxia

Vaala, W. E.

doi:10.1016/s0749-0739(17)30374-7

Cited by 32 publications

(35 citation statements)

References 78 publications

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“…One particular situation in which foals can become substantially hypercapnic is with the clinical syndrome of neonatal encephalopathy. 18,19 A noninvasive method of estimating Paco 2 and detecting hypercapnia or hypocapnia would improve clinical evaluation and monitoring of ill foals with underlying ventilatory or pulmonary disorders and would guide treatment while avoiding frequent arteriopuncture. Results of this study support the use of Petco 2 monitoring as an estimate of Paco 2 in ill neonatal foals on the basis of a significant and strong correlation and relatively good agreement between the 2 measurements.…”

Section: Discussionmentioning

confidence: 99%

Agreement between arterial partial pressure of carbon dioxide and saturation of hemoglobin with oxygen values obtained by direct arterial blood measurements versus noninvasive methods in conscious healthy and ill foals

Wong¹,

Alcott²,

Wang³

et al. 2011

javma

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Objective-To determine agreement between indirect measurements of end-tidal partial pressure of carbon dioxide (Petco2) and saturation of hemoglobin with oxygen as measured by pulse oximetry (Spo2) with direct measurements of Paco2 and calculated saturation of hemoglobin with oxygen in arterial blood (Sao2) in conscious healthy and ill foals. Design-Validation study. Animals-10 healthy and 21 ill neonatal foals. Procedures-Arterial blood gas analysis was performed on healthy and ill foals examined at a veterinary teaching hospital to determine direct measurements of Paco2 and Pao2 along with Sao2. Concurrently, Petco2 was measured with a capnograph inserted into a naris, and Spo2 was measured with a reflectance probe placed at the base of the tail. Paired values were compared by use of Pearson correlation coefficients, and level of agreement was assessed with the Bland-Altman method. Results-Mean ± SD difference between Paco2 and Petco2 was 0.1 ± 5.0 mm Hg. There was significant strong correlation (r = 0.779) and good agreement between Paco2 and Petco2. Mean ± SD difference between Sao2 and Spo2 was 2.5 ± 3.5%. There was significant moderate correlation (r = 0.499) and acceptable agreement between Sao2 and Spo2.

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Section: Discussionmentioning

confidence: 99%

Agreement between arterial partial pressure of carbon dioxide and saturation of hemoglobin with oxygen values obtained by direct arterial blood measurements versus noninvasive methods in conscious healthy and ill foals

Wong¹,

Alcott²,

Wang³

et al. 2011

javma

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“…Most preventative measures and therapies target the birth asphyxia group, as there is a limited time period after insult to prevent or reduce injury, and often with antepartum injury that period has passed by the time the infant is born . Risk factors for the development of hypoxic brain injury in foals include prolonged dystocia, premature placental separation (red bag delivery), and need for resuscitation after cesarean section . Recently, the term neonatal encephalopathy (NE) has been used to encompass all neonatal foals that exhibit neurological abnormalities.…”

Section: Etiologymentioning

confidence: 99%

Hypoxic Ischemic Encephalopathy—What Can We Learn from Humans?

Dickey

Long

Hunt

2011

Veterinary Internal Medicne

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Hypoxic ischemic encephalopathy (HIE) is a condition that occurs in both human newborns and foals. The condition is the subject of extensive current research in human infants, but there have been no direct studies of HIE in foals, and hence, knowledge of the condition has been extrapolated from studies in humans and other animal models. The purpose of this review article is to highlight the most up-to-date and relevant research in the human field, and discuss how this potentially might have an impact in the management of foals with HIE.

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“…A asfixia periparto foi associada, entre outros fatores, à distocia, à indução do parto, à cesariana, à gemelaridade e à doença materna grave (Vaala, 1994), enquanto a asfixia no período neonatal pode resultar de disfunção cardiorrespiratória grave, de hipertensão pulmonar e da obstrução de vias aéreas.…”

Section: Introductionunclassified

“…Na medicina humana, a oligúria é o sinal clínico mais comum de insuficiência renal aguda, semelhante ao que também é observado em potros asfixiados (Koterba et al, 1990;Vaala, 1994). Outro indício de dano renal isquêmico pode ser obtido por meio do perfil bioquímico do animal, a partir de elevadas concentrações séricas de creatinina (Kaneko, 2008).…”

Section: Introductionunclassified

“…As concentrações séricas de creatinina foram significativamente mais altas no grupo PRE em relação ao PNDEX no M60min, M24h e M48h e, em relação ao PN, no M24h e M48h. Durante a asfixia, a redistribuição do fluxo sanguíneo frequentemente ocasiona menor perfusão renal e necrose tubular aguda (Koterba et al, 1990;Vaala, 1994 Res., v.61, p.299-304, 2000. …”

Section: Introductionunclassified

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Parâmetros hematológicos e perfil bioquímico renal de cordeiros nascidos a termo e prematuros

Feitosa¹,

Alcindo²,

Narciso³

et al. 2017

Arq. Bras. Med. Vet. Zootec.

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 RESUMOO objetivo do presente estudo foi avaliar as variáveis hematológicas e o perfil bioquímico renal sérico de cordeiros nascidos a termo e prematuros do nascimento às 48 horas de vida, bem como verificar a influência da dexametasona sobre tais variáveis. Foram constituídos quatros grupos experimentais: PN (cordeiros nascidos de parto normal, n=15, média de 146 dias); PNDEX (cordeiros nascidos de parto normal cujas mães receberam 16mg de dexametasona aos 141 de gestação, n=8, média de 143 dias); PRE (cordeiros prematuros nascidos de cesarianas aos 138 dias de gestação, n=10) e PREDEX (cordeiros prematuros nascidos de cesarianas aos 138 dias de gestação cujas mães receberam 16mg de dexametasona dois dias antes, n=9). Os valores médios do volume globular e de hemoglobina diminuíram ao longo das 48 horas de observação, nos quatro grupos experimentais, porém dentro dos limites fisiológicos para a espécie. Houve variação da concentração plasmática de proteínas totais em todos os momentos, sendo os menores valores no grupo PRE. A contagem leucocitária foi mais alta no grupo PN apenas no M24h. Ao longo do período, apenas o grupo PN mostrou diferença entre o M24h e os demais momentos, e o grupo PRE apresentou os menores valores de neutrófilos no M0h, M15min e M60min. As concentrações séricas de creatinina foram mais altas no grupo PRE no M60min, M24h e M48h. Em todos os grupos, houve diminuição no M24h e M48h. Os parâmetros avaliados foram afetados pela prematuridade na espécie ovina e a dexametasona teve influência positiva sobre a taxa de sobrevivência dos animais prematuros.Palavras-chave: ovinos, bioquímico, hematologia, prematuros ABSTRACT

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Peripartum Asphyxia

Cited by 32 publications

References 78 publications

Agreement between arterial partial pressure of carbon dioxide and saturation of hemoglobin with oxygen values obtained by direct arterial blood measurements versus noninvasive methods in conscious healthy and ill foals

Agreement between arterial partial pressure of carbon dioxide and saturation of hemoglobin with oxygen values obtained by direct arterial blood measurements versus noninvasive methods in conscious healthy and ill foals

Hypoxic Ischemic Encephalopathy—What Can We Learn from Humans?

Parâmetros hematológicos e perfil bioquímico renal de cordeiros nascidos a termo e prematuros

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