Periostin plays a key role in maintaining the osteogenic abilities of dental follicle stem cells in the inflammatory microenvironment

Wei, Xiuqun; Liu, Qian; Liu, Li; Tian, Weidong; Wu, Yafei; Guo, Shujuan

doi:10.1016/j.archoralbio.2023.105737

Cited by 2 publications

(1 citation statement)

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“…Their research demonstrated the formation of functional periodontal ligament-like structures, offering a promising avenue for treating severe periodontitis [ 64 ]. Periostin, a potent biomolecule for periodontitis homeostasis, is shown to be highly expressed by DFSCs and plays an important role in DFSCs’ osteogenic abilities [ 65 ]. DFSCs have been validated to stimulate periodontal regeneration in an inflammatory microenvironment through the regulation of macrophages via human recombinant periostin loaded into the collagen matrix [ 66 ].…”

Section: Mesenchymal Stem Cellsmentioning

confidence: 99%

Mesenchymal Stem Cells in Soft Tissue Regenerative Medicine: A Comprehensive Review

et al. 2023

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Soft tissue regeneration holds significant promise for addressing various clinical challenges, ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue regeneration. Mesenchymal stem cells (MSCs) have emerged as a promising tool in regenerative medicine due to their unique characteristics and potential to differentiate into multiple cell lineages. This comprehensive review explores the role of MSCs in different aspects of soft tissue regeneration, including their application in craniofacial and oral soft tissue regeneration, nerve regeneration, blood vessel regeneration, muscle regeneration, and fibrous tissue regeneration. By examining the latest research findings and clinical advancements, this article aims to provide insights into the current state of MSC-based therapies in soft tissue regenerative medicine.

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Section: Mesenchymal Stem Cellsmentioning

confidence: 99%