Periostin – A Forward Step in Periodontal Biomarkers – A Narrative Review

Abstract

Various biomarkers of periodontal disease are involved in either disease pathogenesis or tissue damage. The main aim of biomarkers research in Periodontology is to provide a significant impact on clinical diagnosis as well as treatment outcomes. Periostin, a microcellular protein is one of the novel biomarkers which is expressed mostly in collagen rich tissues. Its role in systemic health and disease has been studied for many years. Periostin plays a major role in collagen development, cell migration, wound healing and repair and also regulates periodontal pathogenesis. This review focuses on the different aspects of periostin in periodontal health and disease. Keywords: Periostin, Biomarker, Periodontitis, Periodontal regeneration